# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA928073 | F | Cytotoxicity against human NCI-H187 cells at 10 ug/mL | Homo sapiens | 14 | ALA1144725 | cell-based format | Scientific Literature | |
2. | ALA933624 | F | Cytotoxicity against human breast cancer cells at 10 ug/mL | Homo sapiens | 14 | ALA1144725 | cell-based format | Scientific Literature | |
3. | ALA941104 | B | Inhibition of HIV1 reverse transcriptase | Human immunodeficiency virus 1 | 8 | ALA1149052 | single protein format | Scientific Literature | |
4. | ALA941105 | B | Inhibition of HIV2 reverse transcriptase | Human immunodeficiency virus 2 | 6 | ALA1149052 | assay format | Scientific Literature | |
5. | ALA2060534 | B | Inhibition of SARS coronavirus nsP13 helicase activity expressed in Escherichia coli Rosetta assessed inhibition of DNA unwinding activity at 10 uM by FRET assay | SARS coronavirus | 62 | ALA2057104 | assay format | Scientific Literature | |
6. | ALA2060535 | B | Inhibition of HCV NS3 helicase overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of DNA unwinding activity at 10 uM by FRET assay | Hepatitis C virus | 62 | ALA2057104 | assay format | Scientific Literature | |
7. | ALA2060537 | B | Inhibition of HCV NS3 helicase ATP hydrolysis activity overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of inorganic phosphate release by AM/MG-based colometric analysis in the presence of M13 ssDNA | Hepatitis C virus | 62 | ALA2057104 | assay format | Scientific Literature | |
8. | ALA3635921 | B | Inhibition of human IDH1 R132H mutant expressed in IPTG-induced Escherichia coli BL21 cells assessed as oxidation of NADPH to NADP+ after 5 mins by spectrophotometry | Homo sapiens | 55 | ALA3632508 | cell-based format | Scientific Literature | |
9. | ALA3635922 | B | Inhibition of human IDH1 expressed in IPTG-induced Escherichia coli BL21 cells assessed as reduction of NADP+ to NADPH after 5 mins by spectrophotometry | Homo sapiens | 55 | ALA3632508 | cell-based format | Scientific Literature | |
10. | ALA4202382 | F | Antineuroinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production measured after 24 hrs by Griess assay | Mus musculus | 18 | ALA4196247 | cell-based format | Scientific Literature | |
11. | ALA4202383 | A | Cytotoxicity against mouse BV2 cells assessed as reduction in cell viability at 1 to 100 uM after 24 hrs by MTT assay | Mus musculus | 17 | ALA4196247 | cell-based format | Scientific Literature | |
12. | ALA4337638 | B | Inhibition of human DNA ligase 1 using 52-mer DNA/25-mer DNA/27-mer DNA as substrate by fluorescence assay | Homo sapiens | 11 | ALA4334494 | single protein format | Scientific Literature |