| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA923467 | F | Inhibition of TPA-induced skin tumor promotion in mouse assessed as reduction in number of skin papillomas at 3.3 uM after 40 mins | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA923468 | F | Effect on TPA-induced skin tumor promotion in human HeLa cells assessed as inhibition of 32Pi incorporation into phospholipids at 3.3 uM after 40 mins | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA923469 | B | Inhibition of TPA-stimulated phosphorylation of 47K-Da human platelet protein | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 4. | ALA923470 | F | Antiproliferative activity against mouse +SA mammary epithelial cells at 15 to 40 uM after 4 days by MTT assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 5. | ALA2410861 | T | Toxicity in Sprague-Dawley rat hippocampal slice at 10 uM measured after 1 hr by electrophysiological assay | Rattus norvegicus | 5 | tissue-based format | Scientific Literature | ||
| 6. | ALA2410981 | F | Neuroprotective activity in Sprague-Dawley rat hippocampal slice assessed as reversal of DFP-induced damage at 10 uM measured after 2 hrs by electrophysiological assay | Rattus norvegicus | 7 | tissue-based format | Scientific Literature | ||
| 7. | ALA2410983 | F | Neuroprotective activity in Sprague-Dawley rat hippocampal slice assessed as reversal of DFP-induced damage at 10 uM compound treated 30 mins post DFP-challenge measured after 1 hr by electrophysiological assay | Rattus norvegicus | 2 | tissue-based format | Scientific Literature | ||
| 8. | ALA4055515 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as reduction in tumor size at 40 mg/kg, ip administered thrice per week for 20 days measured on day 30 relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA4055516 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as reduction in tumor size at 40 mg/kg, ip administered thrice per week for 20 days measured on day 24 relative to control | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA4055517 | F | In vivo inhibition of VEGFR2 phosphorylation in athymic nude mouse tumor homogenate xenografted with human MDA-MB-231 cells at 40 mg/kg, ip administered thrice per week for 20 days by Western blot analysis relative to control | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA4055518 | F | Antitumor activity against human MDA-MB-231 cells xenografted in athymic nude mouse assessed as reduction in formation of blood vessel red batches in tumor at 40 mg/kg, ip administered thrice per week for 20 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA4055520 | F | Antiproliferative activity against human BT474 cells by MTT assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 13. | ALA4055521 | B | Inhibition of VEGFR2 phosphorylation in human MDA-MB-231 cells at 20 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 14. | ALA4055522 | B | Inhibition of VEGFR2 in human MDA-MB-231 cells assessed as downregulation of phosphorylated paxillin levels at 20 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 15. | ALA4055523 | B | Inhibition of VEGFR2 in human MDA-MB-231 cells assessed as downregulation of phosphorylated FAK levels at 20 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 16. | ALA4055524 | B | Inhibition of VEGFR2 phosphorylation in human MDA-MB-231 cells at 50 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4055525 | B | Inhibition of VEGFR2 in human MDA-MB-231 cells assessed as downregulation of phosphorylated paxillin levels at 50 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4055526 | B | Inhibition of VEGFR2 in human MDA-MB-231 cells assessed as downregulation of phosphorylated FAK levels at 50 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 19. | ALA4055527 | B | Inhibition of VEGFR2 phosphorylation in human BT474 cells at 20 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 20. | ALA4055528 | B | Inhibition of VEGFR2 in human BT474 cells assessed as downregulation of phosphorylated paxillin levels at 20 uM by Western blot analysis | Homo sapiens | 1 | cell-based format | Scientific Literature |
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