# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA937605 | B | Displacement of [3H]PGE2 from human PGE2-EP1 receptor expressed in CHO-K1 cells | Homo sapiens | 55 | ALA1143088 | cell-based format | Scientific Literature | |
2. | ALA937606 | P | Distribution coefficient, logD at pH 7.4 | 50 | ALA1143088 | small-molecule physicochemical format | Scientific Literature | ||
3. | ALA937607 | A | Metabolic stability assessed as intrinsic clearance in rat liver microsomes assessed per gram liver | Rattus norvegicus | 16 | ALA1143088 | microsome format | Scientific Literature | |
4. | ALA937608 | A | Clearance in blood in rat at 10 mL/h/kg, iv | Rattus norvegicus | 14 | ALA1143088 | organism-based format | Scientific Literature | |
5. | ALA937609 | A | Volume of distribution at steady state in rat at 10 mL/h/kg, iv | Rattus norvegicus | 14 | ALA1143088 | organism-based format | Scientific Literature | |
6. | ALA937610 | A | Half life in rat at 10 mL/h/kg, iv | Rattus norvegicus | 14 | ALA1143088 | organism-based format | Scientific Literature | |
7. | ALA1022751 | B | Displacement of [H3PGE2 from human EP1 receptor expressed in CHOK1 cells | Homo sapiens | 38 | ALA1155060 | cell-based format | Scientific Literature | |
8. | ALA1022753 | A | Metabolic stability assessed as intrinsic clearance in rat liver microsomes | Rattus norvegicus | 5 | ALA1155060 | microsome format | Scientific Literature | |
9. | ALA1022754 | A | Blood clearance in rat at 1 mg/kg, iv | Rattus norvegicus | 5 | ALA1155060 | organism-based format | Scientific Literature | |
10. | ALA1022755 | A | Volume of distribution at steady state in rat at 1 mg/kg, iv | Rattus norvegicus | 5 | ALA1155060 | organism-based format | Scientific Literature | |
11. | ALA1022756 | A | Half life in rat at 1 mg/kg, iv | Rattus norvegicus | 5 | ALA1155060 | organism-based format | Scientific Literature | |
12. | ALA1022766 | P | Lipophilicity, log D of the compound | 3 | ALA1155060 | small-molecule physicochemical format | Scientific Literature | ||
13. | ALA1022769 | P | Solubility in water after 0.5 hrs | 2 | ALA1155060 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA1022772 | P | Solubility in simulated gastric fluid after 0.5 hrs | 2 | ALA1155060 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA1022775 | P | Solubility in fasted state simulated intestinal fluid after 0.5 hrs | 2 | ALA1155060 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA1022778 | P | Solubility in fed state simulated intestinal fluid after 0.5 hrs | 2 | ALA1155060 | small-molecule physicochemical format | Scientific Literature | ||
17. | ALA5121331 | P | Thermodynamic aqueous solubility of the compound | 163 | ALA5120754 | small-molecule physicochemical format | Scientific Literature | ||
18. | ALA5121339 | F | Antagonist activity at EP1 receptor (unknown origin) | Homo sapiens | 2 | ALA5120754 | assay format | Scientific Literature |