# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1052237 | Binding | Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Homo sapiens | 9 | ALA1154768 | cell-based format | Scientific Literature | |
2. | ALA1055621 | Binding | Inhibition of [3H]CGS21680 binding to human adenosine A2A receptor expressed in HEK293 cells at 10 uM after 60 mins by liquid scintillation counting | Homo sapiens | 12 | ALA1154768 | cell-based format | Scientific Literature | |
3. | ALA1052922 | Binding | Displacement of [125I]AB-MECA from human recombinant adenosine A3 receptor expressed in CHO cells after 60 mins by liquid scintillation counting | Homo sapiens | 28 | ALA1154768 | cell-based format | Scientific Literature | |
4. | ALA1052924 | Functional | Agonist activity at human recombinant adenosine A3 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP production at 10 uM treated 45 mins before forskolin challenge measured after 15 mins by radioimmunoassay relative to NECA | Homo sapiens | 28 | ALA1154768 | cell-based format | Scientific Literature | |
5. | ALA1053708 | Binding | Binding affinity to rat adenosine A3 receptor expressed in CHO cells | Rattus norvegicus | 4 | ALA1154768 | cell-based format | Scientific Literature | |
6. | ALA935755 | Binding | Displacement of [125I]N6-(4-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A1 receptor expressed in HEK293 cells | Mus musculus | 23 | ALA1145629 | cell-based format | Scientific Literature | |
7. | ALA935757 | Binding | Displacement of [125I]N6-(-amino-3-iodobenzyl)adenosine-5'-N-methyl-uronamide from mouse recombinant adenosine A3 receptor expressed in HEK293 cells | Mus musculus | 23 | ALA1145629 | cell-based format | Scientific Literature | |
8. | ALA935758 | Binding | Displacement of radioligand from human adenosine A1 receptor expressed in CHO cells | Homo sapiens | 23 | ALA1145629 | cell-based format | Scientific Literature | |
9. | ALA923557 | Binding | Displacement of radioligand from human adenosine A3 receptor expressed in CHO cells | Homo sapiens | 23 | ALA1145629 | cell-based format | Scientific Literature | |
10. | ALA923561 | Binding | Displacement of radioligand from human A2A adenosine receptor expressed in HEK293 cells at 10 uM | Homo sapiens | 13 | ALA1145629 | cell-based format | Scientific Literature | |
11. | ALA923562 | Binding | Displacement of [3H]2-[p-(2-carboxyethyl)phenyl-ethylamino]-5'-N-ethylcarbox-amidoadenosine from mouse recombinant adenosine A2A receptor expressed in HEK293 at 100 uM | Mus musculus | 14 | ALA1145629 | cell-based format | Scientific Literature | |
12. | ALA923563 | Binding | Selectivity for mouse adenosine A3 receptor over mouse adenosine A1 receptor | Mus musculus | 23 | ALA1145629 | assay format | Scientific Literature | |
13. | ALA923564 | Binding | Selectivity for human adenosine A3 receptor over human adenosine A1 receptor | Homo sapiens | 23 | ALA1145629 | assay format | Scientific Literature | |
14. | ALA923566 | Functional | Agonist activity at human adenosine A3 receptor expressed in CHO cells by [35S]GTPgammaS binding assay | Homo sapiens | 2 | ALA1145629 | cell-based format | Scientific Literature |