# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1816225 | F | Antimalarial activity Plasmodium falciparum D6 after 72 hrs by SYBR Green I based fluorescence assay | Plasmodium falciparum | 61 | organism-based format | Scientific Literature | ||
2. | ALA1816226 | F | Antimalarial activity multidrug-resistant Plasmodium falciparum Dd2 after 72 hrs by SYBR Green I based fluorescence assay | Plasmodium falciparum | 57 | organism-based format | Scientific Literature | ||
3. | ALA1816227 | T | Toxicity in C57BL/6J mouse splenic lymphocytes after 72 hrs by Alamar blue Assay | Mus musculus | 57 | cell-based format | Scientific Literature | ||
4. | ALA936491 | B | Inhibition of BH3 peptide binding to human recombinant BCL-XL by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA936497 | B | Inhibition of BH3 peptide binding to human recombinant MCL1 by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA936498 | B | Inhibition of BH3 peptide binding to human recombinant BCL-w by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA936499 | B | Inhibition of BH3 peptide binding to human recombinant A1 by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA936500 | B | Inhibition of BH3 peptide binding to human recombinant BCL-b by fluorescence polarization assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA936501 | F | Inhibition of MCL1-BAK interaction in mitochondria of human SKMel5 cells at 10 nM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
10. | ALA936502 | F | Release of cytochrome c in mitochondria of human KB cells at 2 uM | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
11. | ALA936503 | F | Reduction in MCL1-BAK interaction in mitochondria of human SKMel5 cells at 1 uM after 5 hrs by immunoprecipitation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA936504 | F | Disruption of BCL2-BIM interaction in mitochondria of human SKMel5 cells 5 hrs by immunoprecipitation | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
13. | ALA936506 | F | Growth inhibition of W301 Saccharomyces cerevisiae at 50 uM | Saccharomyces cerevisiae | 1 | organism-based format | Scientific Literature | ||
14. | ALA936507 | F | Antagonism of BAX/BAK dependent BCL pathway-mediated inhibition of Saccharomyces cerevisiae W301 | Saccharomyces cerevisiae | 1 | organism-based format | Scientific Literature | ||
15. | ALA936509 | F | Antagonism of BCL pathway-mediated inhibition of Saccharomyces cerevisiae W301 in absence of BAX/BAK | Saccharomyces cerevisiae | 1 | organism-based format | Scientific Literature | ||
16. | ALA924820 | F | Inhibition of apoptosis in Bax and Bak double knock out E1A/p53DN-transformed mouse kidney epithelial cells assessed as caspase-3 activation at 2.0 uM | Mus musculus | 1 | cell-based format | Scientific Literature | ||
17. | ALA924821 | F | Inhibition of apoptosis in Bax and Bak double knock out E1A/p53DN-transformed mouse kidney epithelial cells assessed as DNA cleavage into oligonucleotide fragment | Mus musculus | 1 | cell-based format | Scientific Literature | ||
18. | ALA924822 | F | Induction of apoptosis in mouse Eu-Myc cells overexpressing MCL1 assessed as inhibition of colony formation at 1 uM | Mus musculus | 2 | cell-based format | Scientific Literature | ||
19. | ALA924823 | F | Induction of apoptosis in mouse Eu-Myc cells overexpressing BCL2 assessed as inhibition of colony formation at 1 uM | Mus musculus | 2 | cell-based format | Scientific Literature | ||
20. | ALA924824 | F | Induction of apoptosis in mouse Eu-Myc cells overexpressing A1 assessed as inhibition of colony formation at 1 uM | Mus musculus | 2 | cell-based format | Scientific Literature |