# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2015460 | B | Inhibition of human recombinant beta-glucocerebrosidase assessed as 4-methyumbelliferone formation after 30 mins by spectrophotometric analysis at pH 7 | Homo sapiens | 7 | single protein format | Scientific Literature | ||
2. | ALA2015461 | B | Inhibition of human recombinant beta-glucocerebrosidase assessed as 4-methyumbelliferone formation after 30 mins by spectrophotometric analysis at pH 5.2 | Homo sapiens | 6 | single protein format | Scientific Literature | ||
3. | ALA2015462 | B | Competitive inhibition of human recombinant beta-glucocerebrosidase assessed as 4-methyumbelliferone formation after 30 mins by Lineweaver-Burk plot analysis at pH 5.2 | Homo sapiens | 7 | single protein format | Scientific Literature | ||
4. | ALA2015584 | B | Inhibition of beta-glucocerebrosidase in human fibroblasts assessed as stabilization ratio at 100 uM after 1 hr thermal denaturation at 48 degC by spectrophotometric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA2015586 | B | Inhibition of wild type beta-glucocerebrosidase in human fibroblasts assessed as 4-methyumbelliferone formation at 50 uM after 24 hrs by fluorimetric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
6. | ALA2015592 | B | Increase in beta-glucocerebrosidase N370S mutant activity in lymphoblasts obtained from Gaucher disease patient at 5 uM after 3 days by fluorimetric analysis | Homo sapiens | 1 | single protein format | Scientific Literature | ||
7. | ALA2015597 | B | Increase in beta-glucocerebrosidase L444P mutant activity in lymphoblasts obtained from Gaucher disease patient after 3 days by fluorimetric analysis | Homo sapiens | 2 | single protein format | Scientific Literature | ||
8. | ALA936745 | B | Inhibition of recombinant wild-type glucocerebrosidase | 27 | single protein format | Scientific Literature | |||
9. | ALA936749 | B | Inhibition of rice alpha-glucosidase | Oryza sativa | 1 | assay format | Scientific Literature | ||
10. | ALA936751 | B | Increase in glucocerebrosidase activity in human N370S mutant cells at 40 uM by pulse-chase assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
11. | ALA936755 | B | Increase in glucocerebrosidase activity in human N370S mutant cells at 13.3 uM by pulse-chase assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
12. | ALA921767 | F | Increase in glucocerebrosidase protein localization in lysosomes of human N370S cells at 40 uM | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
13. | ALA980732 | B | Activation of beta-glucocerebrosidase N370S mutant in Goucher lymphoblasts cocultured with HL60 cells at 1 uM after 3 days relative to control | 1 | cell-based format | Scientific Literature | |||
14. | ALA1118770 | B | Inhibition of recombinant beta-glucocerebrosidase at pH 7.4 after 10 mins by fluorimetry | 15 | single protein format | Scientific Literature | |||
15. | ALA1118771 | B | Inhibition of recombinant beta-glucocerebrosidase at pH 5.2 after 10 mins by fluorimetry | 16 | single protein format | Scientific Literature | |||
16. | ALA1118256 | B | Competitive inhibition of beta-glucocerebrosidase at pH 5.2 by Lineweaver-Burke plot analysis | 16 | single protein format | Scientific Literature | |||
17. | ALA1118457 | B | Binding affinity to recombinant beta-glucocerebrosidase assessed as enzymatic activity at 50 uM after 20 mins by thermal stabilization assay relative to control | 8 | single protein format | Scientific Literature | |||
18. | ALA1118458 | B | Binding affinity to recombinant beta-glucocerebrosidase assessed as enzymatic activity at 50 uM after 40 mins by thermal stabilization assay relative to control | 8 | single protein format | Scientific Literature | |||
19. | ALA1118459 | B | Binding affinity to recombinant beta-glucocerebrosidase assessed as enzymatic activity at 50 uM after 60 mins by thermal stabilization assay relative to control | 8 | single protein format | Scientific Literature | |||
20. | ALA1118460 | B | Binding affinity to recombinant beta-glucocerebrosidase assessed as enzymatic activity at 100 uM after 20 mins by thermal stabilization assay relative to control | 8 | single protein format | Scientific Literature |