PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active
PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active
PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active
PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active
PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active
Antimicrobial activity against Enterobacterales producing KPC assessed as reduction in microbial growth measured after 16 to 20 hrs in presence of avibactam by broth microdilution method
Antimicrobial activity against Enterobacterales producing NDM assessed as reduction in microbial growth measured after 16 to 20 hrs in presence of avibactam by broth microdilution method
Antimicrobial activity against Enterobacterales producing VIM assessed as reduction in microbial growth measured after 16 to 20 hrs in presence of avibactam by broth microdilution method
Antimicrobial activity against Enterobacterales producing OXA-48 assessed as reduction in microbial growth measured after 16 to 20 hrs in presence of avibactam by broth microdilution method
Antibacterial activity against Escherichia coli NIHJ JC-2 strain assessed as reduction in microbial growth incubated for 16 to 20 hrs in presence of avibactam by broth microdilution method
Antibacterial activity against Escherichia coli SR34100 producing class A beta lactamase, CTX-M-15 assessed as reduction in microbial growth incubated for 16 to 20 hrs in presence of avibactam by broth microdilution method
Antibacterial activity against Enterobacter cloacae IR32 producing class B beta-lactamase, NDM-1 assessed as reduction in microbial growth incubated for 16 to 20 hrs in presence of avibactam by broth microdilution method
Antibacterial activity against Enterobacter cloacae SR36276 producing class C beta lactamase, AmpC assessed as reduction in microbial growth incubated for 16 to 20 hrs in presence of avibactam by broth microdilution method
Antibacterial activity against Klebsiella pneumoniae PLE producing class D beta lactamase, OXA-48 assessed as reduction in microbial growth incubated for 16 to 20 hrs in presence of avibactam by broth microdilution method
Antibacterial activity against Klebsiella pneumoniae JMI:211 producing class A beta lactamase, KPC-2 assessed as reduction in microbial, growth incubated for 16 to 20 hrs in presence of avibactam by broth microdilution method