# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA662211 | Binding | Inhibition of DNA polymerase | 20 | ALA1124020 | single protein format | Scientific Literature | ||
2. | ALA658100 | Binding | Inhibition of DNA polymerase | 19 | ALA1124020 | assay format | Scientific Literature | ||
3. | ALA689612 | Functional | Antiviral activity against HIV-1 was determined; No inhibition | Human immunodeficiency virus 1 | 15 | ALA1124905 | organism-based format | Scientific Literature | |
4. | ALA690203 | Functional | Percentage of diphosphates (DP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | 20 | ALA1124020 | cell-based format | Scientific Literature | ||
5. | ALA690306 | Functional | Percentage of monophosphates (MP) formed in the first step of staggered assay compound was incubated with HSV-1 thymidine kinase for 4 hr | 19 | ALA1124020 | assay format | Scientific Literature | ||
6. | ALA690307 | Functional | Percentage of monophosphates (MP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | 20 | ALA1124020 | cell-based format | Scientific Literature | ||
7. | ALA695970 | Functional | Percentage of triphosphates (TP) in the second step of staggered assay mixture from step 1 was incubated with GMP kinase and crude extract of HSV-1 infected HeLa cells over night | Homo sapiens | 19 | ALA1124020 | cell-based format | Scientific Literature | |
8. | ALA695599 | Functional | Antiviral activity against HSV-1 cell line (concentration required to prevent viral cytopathic effect in half of primary rabbit kidney cell cultures) | Oryctolagus cuniculus | 8 | ALA1124020 | organism-based format | Scientific Literature | |
9. | ALA691501 | Functional | Antiviral activity against HSV-2 cell line (concentration required to prevent viral cytopathic effect in half of primary rabbit kidney cell cultures) | Oryctolagus cuniculus | 7 | ALA1124020 | organism-based format | Scientific Literature | |
10. | ALA694016 | Functional | Antiviral activity against HCMV was determined; No inhibition | Human betaherpesvirus 5 | 15 | ALA1124905 | organism-based format | Scientific Literature | |
11. | ALA848598 | Binding | Ratio of Ki values for guanine and related hypoxanthines in PNP inhibition assay | Rattus norvegicus | 14 | ALA1127601 | single protein format | Scientific Literature | |
12. | ALA832665 | Binding | Inhibitory concentration against herpes simplex virus type 1 thymidine kinase | herpes simplex virus type 1 | 29 | ALA1139534 | single protein format | Scientific Literature | |
13. | ALA832666 | Binding | Inhibitory concentration against herpes simplex virus type 2 thymidine kinase | Human alphaherpesvirus 2 | 29 | ALA1139534 | single protein format | Scientific Literature | |
14. | ALA816091 | Binding | Binding affinity towards HSV-1 thymidine kinase was determined | Human alphaherpesvirus 1 | 2 | ALA1128343 | single protein format | Scientific Literature | |
15. | ALA938411 | Binding | Inhibition of Herpes B virus recombinant thymidine kinase-mediated [3H]TdR phosphorylation | Macacine alphaherpesvirus 1 | 17 | ALA1145504 | single protein format | Scientific Literature | |
16. | ALA938415 | Binding | Activity of Herpes B virus recombinant thymidine kinase at 100 uM | Macacine alphaherpesvirus 1 | 14 | ALA1145504 | single protein format | Scientific Literature | |
17. | ALA766675 | Binding | Tested for its ability to inhibit calf spleen purine nucleoside phosphorylase (PNP) | Bos taurus | 16 | ALA1127601 | tissue-based format | Scientific Literature | |
18. | ALA4370758 | Functional | Antiviral activity against herpes simplex virus 1 KOS infected in HEL cells assessed as reduction in virus-induced cytopathogenicity by microscopic analysis | Human alphaherpesvirus 1 | 24 | ALA4368930 | organism-based format | Scientific Literature | |
19. | ALA4370759 | Functional | Antiviral activity against herpes simplex virus 2 G infected in HEL cells assessed as reduction in virus-induced cytopathogenicity by microscopic analysis | Human alphaherpesvirus 2 | 24 | ALA4368930 | organism-based format | Scientific Literature | |
20. | ALA4370760 | Functional | Antiviral activity against thymidine kinase deficient and aciclovir resistant herpes simplex virus 1 KOS infected in HEL cells assessed as reduction in virus-induced cytopathogenicity by microscopic analysis | Human alphaherpesvirus 1 | 24 | ALA4368930 | organism-based format | Scientific Literature |