# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA923044 | F | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum FCK2 | Plasmodium falciparum | 13 | organism-based format | Scientific Literature | ||
2. | ALA923045 | F | Antimalarial activity against chloroquine-resistant Plasmodium falciparum MP14 | Plasmodium falciparum | 13 | organism-based format | Scientific Literature | ||
3. | ALA1670272 | B | Inhibition of human recombinant His-tagged glyoxalase 1 expressed in Escherichia coli BL21 (DE3) preincubated for 20 mins by Dixon plot analysis | Homo sapiens | 31 | assay format | Scientific Literature | ||
4. | ALA1805646 | F | Growth inhibition of human A549 cells after 48 hrs by sulforhodamine B assay | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
5. | ALA1805651 | B | Inhibition of TNF-alpha-induced NFkappaB nuclear translocation in human A549 cells preincubated for 30 mins before TNFalpha challenge and measured 30 post TNFalpha challenge by fluorescence method | Homo sapiens | 38 | cell-based format | Scientific Literature | ||
6. | ALA1825397 | B | Binding affinity to goat brain tubulin by spectrophotometry | Capra hircus | 2 | assay format | Scientific Literature | ||
7. | ALA1825398 | P | Aqueous solubility of the compound | 1 | small-molecule physicochemical format | Scientific Literature | |||
8. | ALA1825399 | B | Inhibition of goat brain tubulin polymerization assessed as turbidity by UV spectrophotometry | Capra hircus | 8 | assay format | Scientific Literature | ||
9. | ALA1825400 | F | Antiproliferative activity against human HeLa cells assessed as loss of cell viability after 48 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
10. | ALA1825489 | F | Antiproliferative activity against human A549 cells assessed as loss of cell viability after 48 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
11. | ALA1825490 | F | Induction of cell cycle arrest in human HeLa cells assessed as accumulation in G2/M phase at 5 uM after 24 hrs by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
12. | ALA1825493 | F | Cell cycle arrest in nocodazole pre-treated human HeLa cells at 5 uM assessed as accumulation in G2/M phase after 8 hrs by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
13. | ALA1825494 | F | Induction of apoptosis in human A549 cells assessed as apoptotic cells at 5 uM after 48 hrs by FITC-conjugated annexin-V/PI assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
14. | ALA1825495 | F | Induction of apoptosis in human HeLa cells assessed as apoptotic cells at 5 uM after 48 hrs by FITC-conjugated annexin-V/PI assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
15. | ALA1825496 | F | Induction of apoptosis in human A549 cells assessed as abnormality in nuclear DNA at 5 uM by DAPI staining technique | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
16. | ALA1825497 | F | Induction of apoptosis in human HeLa cells assessed as abnormality in nuclear DNA at 5 uM by DAPI staining technique | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
17. | ALA1825498 | F | Disruption of human A549 cell morphology at 2.5 to 5 uM after 24 hrs by phase contrast microscopy | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
18. | ALA1825499 | F | Disruption of human HeLa cell morphology at 2.5 to 5 uM after 24 hrs by phase contrast microscopy | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
19. | ALA1825500 | F | Disruption of interphase microtubule network in human A549 cells at 2.5 uM after 24 hrs by confocal microscopy | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
20. | ALA1825501 | F | Disruption of interphase microtubule network in human HeLa cells at 2.5 uM after 24 hrs by confocal microscopy | Homo sapiens | 2 | cell-based format | Scientific Literature |