# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA699443 | B | Inhibition of integrin alphaIIb-beta3 binding | Homo sapiens | 3 | ALA1134590 | protein complex format | Scientific Literature | |
2. | ALA699444 | B | Dissociation constant for human integrin alphaIIb-beta3 | Homo sapiens | 1 | ALA1134590 | protein complex format | Scientific Literature | |
3. | ALA698534 | F | Inhibition of human platelet aggregation mediated by alpha llb/beta3 interaction with fibrinogen | Homo sapiens | 5 | ALA1129390 | assay format | Scientific Literature | |
4. | ALA819722 | B | Inhibition of alphaV-beta3 interaction with vitronectin | Homo sapiens | 5 | ALA1129390 | protein complex format | Scientific Literature | |
5. | ALA863347 | B | Displacement of [125I]-echistatin from alphavbeta3 integrin receptor | Homo sapiens | 14 | ALA1141196 | protein complex format | Scientific Literature | |
6. | ALA863348 | B | Displacement of [125I]-echistatin from alpha-v-beta-5 integrin receptor | Homo sapiens | 14 | ALA1141196 | protein complex format | Scientific Literature | |
7. | ALA867620 | B | Displacement of [125I]echistatin from AlphaV-beta-3 integrin receptor | Homo sapiens | 15 | ALA1138156 | protein complex format | Scientific Literature | |
8. | ALA867621 | B | Displacement of [125I]echistatin from AlphaV-beta-5 integrin receptor | Homo sapiens | 14 | ALA1138156 | protein complex format | Scientific Literature | |
9. | ALA870197 | B | Displacement of [3H]8-OH-DPAT from human 5HT1A receptor in HEK293 cells | Homo sapiens | 27 | ALA1147799 | cell-based format | Scientific Literature | |
10. | ALA870198 | B | Displacement of [3H]prazosin from adrenergic alpha-1 receptor in rat cerebral cortex cells | Rattus norvegicus | 9 | ALA1147799 | cell-based format | Scientific Literature | |
11. | ALA870199 | B | Selectivity for adrenergic alpha-1 receptor over 5HT1A receptor | 6 | ALA1147799 | assay format | Scientific Literature | ||
12. | ALA870200 | B | Binding affinity to D2 receptor by radioligand binding assay | Homo sapiens | 6 | ALA1147799 | single protein format | Scientific Literature | |
13. | ALA870201 | B | Selectivity for D2 receptor over 5HT1A receptor | Homo sapiens | 4 | ALA1147799 | protein format | Scientific Literature | |
14. | ALA870202 | A | Elimination half life in human | Homo sapiens | 5 | ALA1147799 | organism-based format | Scientific Literature | |
15. | ALA870203 | F | Activity against 5HT1A receptor relative to 5-HT by Gi-[35S]GTP-gamma-S binding assay | Homo sapiens | 4 | ALA1147799 | assay format | Scientific Literature | |
16. | ALA870204 | F | Activity against 5HT1A receptor by Gi-[35S]GTP-gamma-S binding assay | Homo sapiens | 9 | ALA1147799 | assay format | Scientific Literature | |
17. | ALA870205 | A | Half life in Sprague-Dawley rat at 3 mg/kg, po | Rattus norvegicus | 7 | ALA1147799 | organism-based format | Scientific Literature | |
18. | ALA870206 | A | Oral bioavailability in Sprague-Dawley rat at 3 mg/kg, po and 1 mg/kg, iv | Rattus norvegicus | 6 | ALA1147799 | organism-based format | Scientific Literature | |
19. | ALA870207 | B | Displacement of [3H]prazosin from Adrenergic alpha-1 receptor in rat cerebral cortex cells at 1 uM | Rattus norvegicus | 22 | ALA1147799 | cell-based format | Scientific Literature | |
20. | ALA870838 | B | Displacement of [3H]RX 821002 from Adrenergic alpha-2a receptor in rat cerebral cortex cells | Rattus norvegicus | 2 | ALA1147799 | cell-based format | Scientific Literature |