# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA932181 | F | Antiinflammatory activity in mouse J774A.1 cells assessed as inhibition of lipopolysaccharide-induced TNFalpha production pretreated for 2 hrs at 10 uM before LPS challenge | Mus musculus | 17 | cell-based format | Scientific Literature | ||
2. | ALA932182 | F | Antiinflammatory activity in mouse J774A.1 cells assessed as inhibition of lipopolysaccharide-induced IL6 production pretreated for 2 hrs at 10 uM before LPS challenge | Mus musculus | 7 | cell-based format | Scientific Literature | ||
3. | ALA1107089 | B | Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cells at 100 uM | Rattus norvegicus | 22 | assay format | Scientific Literature | ||
4. | ALA1108825 | B | Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomes at 100 uM | Rattus norvegicus | 23 | microsome format | Scientific Literature | ||
5. | ALA1108828 | B | Inhibition of 17beta-HSD3 in human testis microsomes | Homo sapiens | 5 | microsome format | Scientific Literature | ||
6. | ALA1768123 | B | Displacement of [125I]IMPY from amyloid beta (1 to 42) aggregate after 2 hrs by gamma counting | 70 | assay format | Scientific Literature | |||
7. | ALA1771894 | A | Cytotoxic activity against human HeLa cells after 24 to 48 hrs by MTT assay | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
8. | ALA1771895 | F | Antiplasmodial activity against blood stage of chloroquine-resistant Plasmodium falciparum isolate RKL9 infected in human O positive erythrocytes after 48 hrs by SYBR green I-based fluorescence assay | Plasmodium falciparum | 16 | organism-based format | Scientific Literature | ||
9. | ALA1771896 | F | Antiplasmodial activity against blood stage of chloroquine-sensitive Plasmodium falciparum 3D7 infected in human O positive erythrocytes after 48 hrs by SYBR green-I based fluorescence assay | Plasmodium falciparum | 16 | organism-based format | Scientific Literature | ||
10. | ALA2405592 | B | Inhibition of 11beta-HSD2 in human kidney microsomes using [3H]-cortisol as substrate assessed as formation of cortisone at 100 uM after 30 mins by radiometric analysis relative to control | Homo sapiens | 36 | microsome format | Scientific Literature | ||
11. | ALA2405593 | B | Inhibition of 11beta-HSD2 in rat kidney microsomes using [3H]-CORT as substrate assessed as formation of 11-DHC at 100 uM after 30 mins by radiometric analysis relative to control | Rattus norvegicus | 36 | microsome format | Scientific Literature | ||
12. | ALA2405597 | B | Inhibition of human 11beta-HSD1 transfected in CHOP cells at 100 uM relative to control | Homo sapiens | 25 | cell-based format | Scientific Literature | ||
13. | ALA2405599 | B | Inhibition of 11beta-HSD1 in Sprague-Dawley rat leydig cells at 100 uM relative to control | Rattus norvegicus | 21 | assay format | Scientific Literature | ||
14. | ALA2405600 | F | Antiinflammatory activity in mouse J774A1 cells assessed as LPS-induced TNFalpha production at 10 uM incubated 2 hrs prior to LPS challenge measured after 24 hrs by ELISA relative to vehicle-treated control | Mus musculus | 17 | cell-based format | Scientific Literature | ||
15. | ALA2405604 | B | Inhibition of 11beta-HSD1 in rat testis microsomes using [3H]-11-DHC as substrate assessed as formation of CORT at 100 uM after 60 to 90 mins by radiometric analysis relative to control | Rattus norvegicus | 27 | microsome format | Scientific Literature | ||
16. | ALA2405606 | B | Inhibition of 11beta-HSD1 in human liver microsomes using [3H]-cortisone as substrate assessed as formation of cortisol at 100 uM after 60 to 90 mins by radiometric analysis relative to control | Homo sapiens | 26 | microsome format | Scientific Literature | ||
17. | ALA3387643 | F | Increase in permeability of lucifer yellow dye across human Caco2 cells | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
18. | ALA3387644 | F | Increase in permeability of lucifer yellow dye across MDCK cells | Canis lupus familiaris | 10 | cell-based format | Scientific Literature | ||
19. | ALA3387645 | A | Cytotoxicity against MDCK cells assessed as reduction in cell viability | Canis lupus familiaris | 10 | cell-based format | Scientific Literature | ||
20. | ALA3387646 | A | Cytotoxicity against human Caco2 cells assessed as reduction in cell viability | Homo sapiens | 10 | cell-based format | Scientific Literature |