| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA929590 | B | Inhibition of 17beta-HSD1 in human T47D cells assessed as inhibition of transformation of [14C]-estrone into [14C]estrogen at 0.1 uM after 24 hrs | Homo sapiens | 12 | ALA1143127 | cell-based format | Scientific Literature | |
| 2. | ALA929589 | B | Inhibition of 17beta-HSD1 in human T47D cells assessed as inhibition of transformation of [14C]-estrone into [14C]-estrogen at 1 uM after 24 hrs | Homo sapiens | 12 | ALA1143127 | cell-based format | Scientific Literature | |
| 3. | ALA929591 | B | Inhibition of 17beta-HSD1 in human T47D cells assessed as inhibition of transformation of [14C]-estrone into [14C]estrogen at 10 uM after 24 hrs | Homo sapiens | 12 | ALA1143127 | cell-based format | Scientific Literature | |
| 4. | ALA930592 | B | Inhibition of 17beta-HSD1 in human T47D cells assessed as inhibition of transformation of [14C]-estrone into [14C]estrogen | Homo sapiens | 4 | ALA1143127 | cell-based format | Scientific Literature | |
| 5. | ALA930598 | F | Reduction of estrone-induced human T47D cell growth at 0.5 uM after 8 days relative to control | Homo sapiens | 1 | ALA1143127 | cell-based format | Scientific Literature | |
| 6. | ALA930599 | F | Reversal of estrogen-induced proliferation in estrogen-sensitive human MCF7 cells at 0.5 uM after 8 days relative to control | Homo sapiens | 2 | ALA1143127 | cell-based format | Scientific Literature | |
| 7. | ALA930600 | B | Inhibition of 17beta-HSD2 over-expressed in HEK293 cells assessed as inhibition of transformation of [14C]-estrogen into [14C]-estrone at 10 uM | 1 | ALA1143127 | cell-based format | Scientific Literature | ||
| 8. | ALA1832598 | B | Inhibition of 17beta-HSD1 in human T47D cells expressing estrogen receptor assessed as conversion of [14C]-E1 to [14C]-E2 at 5 uM after 24 hrs | Homo sapiens | 2 | ALA1828522 | cell-based format | Scientific Literature | |
| 9. | ALA1832599 | B | Inhibition of 17beta-HSD1 in human T47D cells expressing estrogen receptor assessed as conversion of [14C]-E1 to [14C]-E2 at 0.3 uM after 24 hrs | Homo sapiens | 2 | ALA1828522 | cell-based format | Scientific Literature | |
| 10. | ALA1832601 | F | Estrogenic activity in human T47D cells expressing estrogen receptor assessed as stimulation cell growth at 0.1 uM after 48 hrs relative to control | Homo sapiens | 2 | ALA1828522 | cell-based format | Scientific Literature | |
| 11. | ALA1832602 | F | Estrogenic activity in human T47D cells expressing estrogen receptor assessed as stimulation cell growth at 1 uM after 48 hrs relative to control | Homo sapiens | 2 | ALA1828522 | cell-based format | Scientific Literature | |
| 12. | ALA2208948 | B | Inhibition of 17beta-HSD1 in human T47D cells assessed as decrease in transformation of [14C]estrone to [14C]-estradiol after 24 hrs by thin layer chromatography | Homo sapiens | 5 | ALA2203102 | cell-based format | Scientific Literature | |
| 13. | ALA2208950 | B | Inhibition of 17beta-HSD1 in human T47D cells assessed as decrease in transformation of [14C]estrone to [14C]-estradiol at 0.1 uM after 24 hrs by thin layer chromatography | Homo sapiens | 5 | ALA2203102 | cell-based format | Scientific Literature | |
| 14. | ALA2208951 | B | Inhibition of 17beta-HSD1 in human T47D cells assessed as decrease in transformation of [14C]estrone to [14C]-estradiol at 0.01 uM after 24 hrs by thin layer chromatography | Homo sapiens | 5 | ALA2203102 | cell-based format | Scientific Literature | |
| 15. | ALA3111002 | A | Inhibition of CYP3A4 (unknown origin) by fluorescence assay | Homo sapiens | 3 | ALA3108749 | single protein format | Scientific Literature | |
| 16. | ALA3111003 | B | Inhibition of 17-beta HSD12 (unknown origin) transfected in HEK293 cells using [14C]E1 as substrate at 10 uM | Homo sapiens | 2 | ALA3108749 | cell-based format | Scientific Literature | |
| 17. | ALA3111004 | B | Inhibition of 17-beta HSD7 (unknown origin) transfected in HEK293 cells using [14C]E1 as substrate at 10 uM | Homo sapiens | 3 | ALA3108749 | cell-based format | Scientific Literature | |
| 18. | ALA3111005 | B | Inhibition of 17-beta HSD2 (unknown origin) transfected in HEK293 cells using [14C]E2 as substrate at 10 uM | Homo sapiens | 2 | ALA3108749 | cell-based format | Scientific Literature | |
| 19. | ALA3111007 | B | Inhibition of 17-beta HSD1 in human T47D cells assessed as transformation of [14C]E1 to [14C]E2 after 24 hrs by thin layer chromatography | Homo sapiens | 5 | ALA3108749 | cell-based format | Scientific Literature | |
| 20. | ALA3111010 | F | Cytotoxicity against human estrogen-starved estrogen-sensitive MCF7 cells assessed as cell growth at 1 uM after 7 days by MTS assay relative to control | Homo sapiens | 20 | ALA3108749 | cell-based format | Scientific Literature |
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