| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA945949 | F | Inhibition of UVB irradiation-induced MMP1 production in human dermal fibroblasts at 5 uM after 48 hrs | Homo sapiens | 5 | ALA1142306 | cell-based format | Scientific Literature | |
| 2. | ALA945950 | F | Inhibition of UVB irradiation-induced MMP1 production in human dermal fibroblasts at 20 uM after 48 hrs | Homo sapiens | 1 | ALA1142306 | cell-based format | Scientific Literature | |
| 3. | ALA945953 | F | Inhibition of UVB irradiation-induced MMP1 production in human dermal fibroblasts at 10 uM after 48 hrs | Homo sapiens | 1 | ALA1142306 | cell-based format | Scientific Literature | |
| 4. | ALA945955 | F | Growth inhibition of UVB irradiated human dermal fibroblasts at 20 uM | Homo sapiens | 1 | ALA1142306 | cell-based format | Scientific Literature | |
| 5. | ALA945957 | F | Decrease in protein content in UVB irradiated human dermal fibroblasts at 20 uM relative to control | Homo sapiens | 1 | ALA1142306 | cell-based format | Scientific Literature | |
| 6. | ALA945960 | F | Decrease in cell viability of UVB irradiated human dermal fibroblasts at 20 uM | Homo sapiens | 1 | ALA1142306 | cell-based format | Scientific Literature | |
| 7. | ALA945961 | B | Inhibition of MMP2 in UVB irradiated human dermal fibroblasts at <5 uM by zymography | Homo sapiens | 5 | ALA1142306 | single protein format | Scientific Literature | |
| 8. | ALA3587905 | B | Inhibition of PTP1B in mouse 3T3L1 cells assessed as stimulation of 2-NBDG uptake preincubated for 24 hrs followed by 2-NBDG addition measured after 30 mins by fluorescence reader analysis | Mus musculus | 7 | ALA3585252 | cell-based format | Scientific Literature | |
| 9. | ALA3587906 | B | Inhibition of PTP1B in mouse 3T3L1 cells assessed as stimulation of 2-NBDG uptake at 10 uM preincubated for 24 hrs followed by 2-NBDG addition measured after 30 mins by fluorescence reader analysis relative to control | Mus musculus | 3 | ALA3585252 | cell-based format | Scientific Literature | |
| 10. | ALA3587907 | A | Cytotoxicity against mouse 3T3L1 cells assessed as inhibition of cell viability at 5 to 10 uM after 48 hrs by MTT assay | Mus musculus | 7 | ALA3585252 | cell-based format | Scientific Literature | |
| 11. | ALA3587908 | B | Inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by microplate reader analysis | Homo sapiens | 9 | ALA3585252 | single protein format | Scientific Literature | |
| 12. | ALA3587976 | B | Mixed-competitive inhibition of human recombinant PTP1B using p-NPP as substrate preincubated for 10 mins followed by substrate addition measured after 20 mins by Lineweaver-Burk/Dixon plot analysis | Homo sapiens | 6 | ALA3585252 | single protein format | Scientific Literature |
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