# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA933867 | B | Inotropic activity at L type calcium channel in guinea pig left atrium assessed as decrease in tension at 100 uM relative to control | Cavia porcellus | 8 | tissue-based format | Scientific Literature | ||
2. | ALA935023 | B | Chronotropic activity at L type calcium channel in guinea pig right atrium assessed as decrease in spontaneous beating at 100 uM relative to control | Cavia porcellus | 5 | tissue-based format | Scientific Literature | ||
3. | ALA935025 | B | Inotropic activity at L type calcium channel in guinea pig left atrium assessed as decrease in tension | Cavia porcellus | 29 | tissue-based format | Scientific Literature | ||
4. | ALA935026 | B | Chronotropic activity at L type calcium channel in guinea pig right atrium assessed as decrease in spontaneous beating | Cavia porcellus | 20 | tissue-based format | Scientific Literature | ||
5. | ALA935027 | B | Activity at L type calcium channel in K+ depolarized guinea pig aortic strip assessed as inhibition of calcium induced contraction at 100 uM | Cavia porcellus | 17 | tissue-based format | Scientific Literature | ||
6. | ALA1817226 | B | Activity at CFTR F508 deletion mutant expressed in forskolin-stimulated FRT cells assessed as maximal increase in iodine influx measured as YFP quenching rate up to 20 uM after 24 hrs by fluorescence assay | 14 | cell-based format | Scientific Literature | |||
7. | ALA1817227 | B | Activity at CFTR F508 deletion mutant expressed in forskolin-stimulated FRT cells assessed as maximal increase in iodine influx measured as YFP quenching rate at 0.2 uM after 24 hrs by fluorescence assay | 32 | cell-based format | Scientific Literature | |||
8. | ALA1816044 | F | Negative ionotropic activity in potassium depolarized guinea pig longitudinal smooth muscle assessed as inhibition of calcium-induced contraction at 5 X 10'-5 M | Cavia porcellus | 3 | assay format | Scientific Literature | ||
9. | ALA1816045 | F | Negative ionotropic activity in potassium depolarized guinea pig longitudinal smooth muscle assessed as inhibition of calcium-induced contraction | Cavia porcellus | 32 | assay format | Scientific Literature | ||
10. | ALA4385684 | B | Inhibition of voltage-dependent L-type calcium channel in human U373MG cells assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of cell viability at 1 uM administered at onset of reperfusion period measured after 16 hrs by alamar blue assay relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
11. | ALA4385685 | B | Inhibition of voltage-dependent L-type calcium channel in human U373MG cells assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of cell viability at 20 uM administered at onset of reperfusion period measured after 16 hrs by alamar blue assay relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
12. | ALA4385686 | B | Inhibition of voltage-dependent L-type calcium channel in human SH-SY5Y cells assessed as protection against glutamate-induced excitotoxicity by measuring recovery of cell viability at 1 uM measured after 24 hrs by alamar blue-based fluorescence method relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
13. | ALA4385687 | B | Inhibition of voltage-dependent L-type calcium channel in human SH-SY5Y cells assessed as protection against glutamate-induced excitotoxicity by measuring recovery of cell viability at 20 uM measured after 24 hrs by alamar blue-based fluorescence method relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
14. | ALA4385688 | B | Inhibition of voltage-dependent L-type calcium channel in Wistar rat brain slices assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of LDH release at 20 uM administered at onset of reperfusion period measured after 90 mins by spectrophotometric assay relative to control | Rattus norvegicus | 20 | tissue-based format | Scientific Literature | ||
15. | ALA4385689 | B | Inhibition of voltage-dependent L-type calcium channel in Wistar rat brain slices assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of edema formation at 20 uM administered at onset of reperfusion period measured after 90 mins relative to control | Rattus norvegicus | 20 | tissue-based format | Scientific Literature |