| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA933941 | B | Inotropic activity at L type calcium channel in guinea pig left atrium assessed as decrease in tension at 50 uM relative to control | Cavia porcellus | 10 | tissue-based format | Scientific Literature | ||
| 2. | ALA935020 | B | Chronotropic activity at L type calcium channel in guinea pig right atrium assessed as decrease in spontaneous beating at 10 uM relative to control | Cavia porcellus | 15 | tissue-based format | Scientific Literature | ||
| 3. | ALA935025 | B | Inotropic activity at L type calcium channel in guinea pig left atrium assessed as decrease in tension | Cavia porcellus | 29 | tissue-based format | Scientific Literature | ||
| 4. | ALA935027 | B | Activity at L type calcium channel in K+ depolarized guinea pig aortic strip assessed as inhibition of calcium induced contraction at 100 uM | Cavia porcellus | 17 | tissue-based format | Scientific Literature | ||
| 5. | ALA935032 | B | Activity at L type calcium channel in K+ depolarized guinea pig longitudinal smooth muscle assessed as inhibition of calcium induced contraction at 10 uM | Cavia porcellus | 4 | assay format | Scientific Literature | ||
| 6. | ALA934086 | B | Activity at L type calcium channel in K+ depolarized guinea pig longitudinal smooth muscle assessed as inhibition of calcium induced contraction | Cavia porcellus | 12 | assay format | Scientific Literature | ||
| 7. | ALA2383742 | B | Displacement of [3H]-PN200-110 from L-type calcium channel dihydropyridine binding site in Wistar rat cortex homogenate after 60 mins by liquid scintillation spectometric analysis | Rattus norvegicus | 12 | tissue-based format | Scientific Literature | ||
| 8. | ALA2383743 | B | Displacement of [3H]-PN200-110 from L-type calcium channel dihydropyridine binding site in Wistar rat cortex homogenate at 100 uM after 60 mins by liquid scintillation spectometric analysis relative to control | Rattus norvegicus | 12 | tissue-based format | Scientific Literature | ||
| 9. | ALA2383746 | B | Displacement of [3H]-PN200-110 from L-type calcium channel in Hartley guinea pig ventricular membrane at 100 uM after 90 mins relative to control | Cavia porcellus | 12 | assay format | Scientific Literature | ||
| 10. | ALA2383747 | B | Displacement of [3H]-PN200-110 from L-type calcium channel in Hartley guinea pig atrial membrane after 90 mins | Cavia porcellus | 11 | cell membrane format | Scientific Literature | ||
| 11. | ALA2383748 | B | Displacement of [3H]-PN200-110 from L-type calcium channel in Hartley guinea pig atrial membrane at 100 uM after 90 mins relative to control | Cavia porcellus | 12 | cell membrane format | Scientific Literature | ||
| 12. | ALA2383885 | B | Displacement of [3H]-PN200-110 from voltage-gated calcium channel subunit alpha Cav1.2a (unknown origin) expressed in HEK293 cells at 100 uM after 90 mins by liquid scintillation counting analysis relative to control | Homo sapiens | 12 | cell-based format | Scientific Literature | ||
| 13. | ALA4385684 | B | Inhibition of voltage-dependent L-type calcium channel in human U373MG cells assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of cell viability at 1 uM administered at onset of reperfusion period measured after 16 hrs by alamar blue assay relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 14. | ALA4385685 | B | Inhibition of voltage-dependent L-type calcium channel in human U373MG cells assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of cell viability at 20 uM administered at onset of reperfusion period measured after 16 hrs by alamar blue assay relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 15. | ALA4385686 | B | Inhibition of voltage-dependent L-type calcium channel in human SH-SY5Y cells assessed as protection against glutamate-induced excitotoxicity by measuring recovery of cell viability at 1 uM measured after 24 hrs by alamar blue-based fluorescence method relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 16. | ALA4385687 | B | Inhibition of voltage-dependent L-type calcium channel in human SH-SY5Y cells assessed as protection against glutamate-induced excitotoxicity by measuring recovery of cell viability at 20 uM measured after 24 hrs by alamar blue-based fluorescence method relative to control | Homo sapiens | 36 | cell-based format | Scientific Literature | ||
| 17. | ALA4385688 | B | Inhibition of voltage-dependent L-type calcium channel in Wistar rat brain slices assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of LDH release at 20 uM administered at onset of reperfusion period measured after 90 mins by spectrophotometric assay relative to control | Rattus norvegicus | 20 | tissue-based format | Scientific Literature | ||
| 18. | ALA4385689 | B | Inhibition of voltage-dependent L-type calcium channel in Wistar rat brain slices assessed as protection against oxygen glucose deprivation/reperfusion-induced injury by measuring recovery of edema formation at 20 uM administered at onset of reperfusion period measured after 90 mins relative to control | Rattus norvegicus | 20 | tissue-based format | Scientific Literature |
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