# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA930770 | B | Inhibition of human MMP13 catalytic domain | Homo sapiens | 32 | ALA1142320 | single protein format | Scientific Literature | |
2. | ALA930771 | B | Inhibition of human MMP13 | Homo sapiens | 30 | ALA1142320 | single protein format | Scientific Literature | |
3. | ALA930772 | A | Clearance in rat | Rattus norvegicus | 10 | ALA1142320 | organism-based format | Scientific Literature | |
4. | ALA931873 | A | Volume of distribution at steady state in rat | Rattus norvegicus | 10 | ALA1142320 | organism-based format | Scientific Literature | |
5. | ALA931874 | A | AUC (0 to infinity) in orally dosed rat | Rattus norvegicus | 10 | ALA1142320 | organism-based format | Scientific Literature | |
6. | ALA931875 | A | Half life in orally dosed rat | Rattus norvegicus | 8 | ALA1142320 | organism-based format | Scientific Literature | |
7. | ALA931876 | A | Oral bioavailability in rat | Rattus norvegicus | 9 | ALA1142320 | organism-based format | Scientific Literature | |
8. | ALA931877 | P | Solubility of the compound | 9 | ALA1142320 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA931878 | B | Inhibition of MMP1 | 2 | ALA1142320 | single protein format | Scientific Literature | ||
10. | ALA931879 | B | Inhibition of MMP2 | 2 | ALA1142320 | single protein format | Scientific Literature | ||
11. | ALA931880 | B | Inhibition of MMP3 catalytic domain | 2 | ALA1142320 | single protein format | Scientific Literature | ||
12. | ALA931881 | B | Inhibition of MMP7 | 2 | ALA1142320 | single protein format | Scientific Literature | ||
13. | ALA931882 | B | Inhibition of MMP8 catalytic domain | 1 | ALA1142320 | single protein format | Scientific Literature | ||
14. | ALA931883 | B | Inhibition of MMP9 | 2 | ALA1142320 | single protein format | Scientific Literature | ||
15. | ALA931884 | B | Inhibition of MMP12 | 2 | ALA1142320 | single protein format | Scientific Literature | ||
16. | ALA931885 | B | Inhibition of MMP14 catalytic domain | 2 | ALA1142320 | single protein format | Scientific Literature | ||
17. | ALA931886 | B | Inhibition of MMP17 catalytic domain | 1 | ALA1142320 | single protein format | Scientific Literature | ||
18. | ALA931887 | A | AUC (0 to 24 hrs) in Sprague-Dawley rat at 2000 mg/kg/day after 14 days | Rattus norvegicus | 3 | ALA1142320 | organism-based format | Scientific Literature | |
19. | ALA931888 | T | Toxicity in Sprague-Dawley rat assessed as musculoskeletal syndrome-like joint fibroplasias at 2000 mg/kg/day | Rattus norvegicus | 2 | ALA1142320 | organism-based format | Scientific Literature | |
20. | ALA931889 | F | Inhibition of tibial plateau cartilage degeneration in New Zealanda white rabbit osteoarthritis model at 10 mg/kg after 35 days | Oryctolagus cuniculus | 1 | ALA1142320 | organism-based format | Scientific Literature |