| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA619475 | A | Reduction in area under curve was determined in DIO mice by oral glucose tolerance test following a single i.p. dose (10 mg/kg, 30 min pre-treatment) | Mus musculus | 2 | organism-based format | Scientific Literature | ||
| 2. | ALA623887 | A | Maximal concentration in rat was determined | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA622875 | A | Reduction in area under curve was determined in fa/fa Zucker rats by oral glucose tolerance test following a single i.p. dose (30 mg/kg, 30 min pre-treatment) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA623063 | A | Oral bioavailability in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA655662 | B | In vitro inhibitory activity against CD45 protein-tyrosine phosphatase | 15 | single protein format | Scientific Literature | |||
| 6. | ALA857422 | B | In vitro inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) over-expressed in intact Sf9 cell assay | 14 | cell-based format | Scientific Literature | |||
| 7. | ALA768521 | B | In vitro inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assay | 15 | single protein format | Scientific Literature | |||
| 8. | ALA936456 | B | Inhibition of PTP1B by fluorescein diphosphate assay | 20 | single protein format | Scientific Literature | |||
| 9. | ALA936457 | B | Inhibition of CD45 by fluorescein diphosphate assay | 19 | single protein format | Scientific Literature | |||
| 10. | ALA1071696 | B | Inhibition of PTP1B | 32 | single protein format | Scientific Literature | |||
| 11. | ALA1071697 | B | Inhibition of TCPTP | 16 | single protein format | Scientific Literature | |||
| 12. | ALA1071699 | B | Selectivity ratio of IC50 for TCPTP to IC50 for PTP1B | 10 | assay format | Scientific Literature | |||
| 13. | ALA2019336 | B | Inhibition of human recombinant PTP1B expressed in Escherichia coli using para-nitrophenyl phosphate as substrate preincubated for 30 mins followed by substrate addition measured by fluorescence analysis | Homo sapiens | 22 | assay format | Scientific Literature | ||
| 14. | ALA2019353 | A | Oral bioavailability in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA4021018 | B | Inhibition of PTP1B (unknown origin) using p-NPP as substrate measured every 30 secs for 15 mins | Homo sapiens | 2 | single protein format | Scientific Literature | ||
| 16. | ALA4021019 | B | Selectivity ratio of IC50 for TCPTP (unknown origin) to IC50 for PTP1B (unknown origin) | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 17. | ALA4371147 | B | Inhibition of PTP1B (unknown origin) expressed in sf9 cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4371148 | A | Cmax in rat | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 19. | ALA4371149 | A | Oral bioavailability in rat | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA4371150 | B | Inhibition of PTP1B (unknown origin) by FDP assay | Homo sapiens | 1 | single protein format | Scientific Literature |
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