| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA930987 | B | Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in HEK293 cells | Homo sapiens | 28 | ALA1141567 | cell-based format | Scientific Literature | |
| 2. | ALA930988 | B | Displacement of [3H]naltrindole from human delta opioid receptor expressed in HEK293 cells | Homo sapiens | 21 | ALA1141567 | cell-based format | Scientific Literature | |
| 3. | ALA930989 | B | Displacement of [3H]diprenorphine from human kappa opioid receptor expressed in HEK293 cells | Homo sapiens | 21 | ALA1141567 | cell-based format | Scientific Literature | |
| 4. | ALA930990 | B | Displacement of [3H]diprenorphine from human mu opioid receptor expressed in CHO cells | Homo sapiens | 21 | ALA1141567 | cell-based format | Scientific Literature | |
| 5. | ALA930991 | B | Selectivity for human NOP receptor over human kappa opioid receptor | Homo sapiens | 21 | ALA1141567 | assay format | Scientific Literature | |
| 6. | ALA930992 | B | Selectivity for human NOP receptor over human mu opioid receptor | Homo sapiens | 21 | ALA1141567 | assay format | Scientific Literature | |
| 7. | ALA1763211 | B | Displacement of [125I]Tyr14-nociceptin from human NOP receptor expressed in human HEK293 cells after 2 hrs by scintillation counting | Homo sapiens | 46 | ALA1759965 | cell-based format | Scientific Literature | |
| 8. | ALA4428189 | B | Binding affinity to human nociceptin opioid receptor | Homo sapiens | 1 | ALA4428025 | single protein format | Scientific Literature | |
| 9. | ALA4428190 | B | Binding affinity to human mu opioid receptor | Homo sapiens | 1 | ALA4428025 | single protein format | Scientific Literature | |
| 10. | ALA4428191 | B | Agonist activity at human nociceptin opioid receptor by GTPgamma(35)S binding assay | Homo sapiens | 1 | ALA4428025 | single protein format | Scientific Literature | |
| 11. | ALA4428212 | A | Oral bioavailability in Wistar rat at 0.3 mg/kg | Rattus norvegicus | 1 | ALA4428025 | organism-based format | Scientific Literature | |
| 12. | ALA4428213 | A | Oral bioavailability in cynomolgus monkey at 0.3 mg/kg | Macaca fascicularis | 1 | ALA4428025 | organism-based format | Scientific Literature | |
| 13. | ALA4428215 | B | Selectivity ratio of Ki for human mu opioid receptor to Ki for human nociceptin opioid receptor | Homo sapiens | 2 | ALA4428025 | assay format | Scientific Literature |
The page will load shortly, Thanks for your patience!