| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA935243 | A | Stability in CD1 mouse liver S9 fraction assessed as prodrug hydrolysis at 20 uM after 5 mins | Mus musculus | 14 | ALA1141628 | subcellular format | Scientific Literature | |
| 2. | ALA935244 | A | Stability in human liver S9 fraction assessed as prodrug hydrolysis at 20 uM after 5 mins | Homo sapiens | 14 | ALA1141628 | subcellular format | Scientific Literature | |
| 3. | ALA935245 | A | Cmax in mouse at 50 mg/kg, po | Mus musculus | 5 | ALA1141628 | organism-based format | Scientific Literature | |
| 4. | ALA935246 | A | Cmax in mouse at 200 mg/kg, po | Mus musculus | 5 | ALA1141628 | organism-based format | Scientific Literature | |
| 5. | ALA935247 | A | AUC (0 to 4 hrs) in mouse at 50 mg/kg, po | Mus musculus | 5 | ALA1141628 | organism-based format | Scientific Literature | |
| 6. | ALA935248 | A | AUC (0 to 4 hrs) in mouse at 200 mg/kg, po | Mus musculus | 5 | ALA1141628 | organism-based format | Scientific Literature | |
| 7. | ALA935249 | A | Ratio of AUC (0 to 4 hrs) in mouse plasma at 200 mg/kg, po to AUC (0 to 4 hrs) in mouse plasma at 50 mg/kg, po | Mus musculus | 5 | ALA1141628 | organism-based format | Scientific Literature | |
| 8. | ALA935250 | A | Inhibition of human CYP1A2 | Homo sapiens | 4 | ALA1141628 | single protein format | Scientific Literature | |
| 9. | ALA935251 | A | Inhibition of human CYP2C9 | Homo sapiens | 4 | ALA1141628 | single protein format | Scientific Literature | |
| 10. | ALA935252 | A | Inhibition of human CYP2C19 | Homo sapiens | 4 | ALA1141628 | single protein format | Scientific Literature | |
| 11. | ALA935253 | A | Inhibition of human CYP2D6 | Homo sapiens | 4 | ALA1141628 | single protein format | Scientific Literature | |
| 12. | ALA935239 | A | Inhibition of human CYP3A4 using 7-benzyl-trifluoromethyl coumarin | Homo sapiens | 4 | ALA1141628 | single protein format | Scientific Literature | |
| 13. | ALA935240 | A | Inhibition of human CYP3A4 using 7-benzyloxyresorufin | Homo sapiens | 4 | ALA1141628 | single protein format | Scientific Literature | |
| 14. | ALA935254 | P | Stability assessed as prodrug degradation at 50 degC for 12 weeks | 1 | ALA1141628 | small-molecule physicochemical format | Scientific Literature | ||
| 15. | ALA935256 | P | Stability assessed as prodrug degradation at pH 4.2 and at 37 degC for 24 hrs | 1 | ALA1141628 | small-molecule physicochemical format | Scientific Literature | ||
| 16. | ALA935255 | P | Aqueous solubility at pH 5.8 | 1 | ALA1141628 | small-molecule physicochemical format | Scientific Literature | ||
| 17. | ALA935257 | F | Antitumor activity against human L2987 cells xenografted po dosed athymic mouse after 14 days | Homo sapiens | 1 | ALA1141628 | organism-based format | Scientific Literature | |
| 18. | ALA935258 | F | Antitumor activity against human L2987 cells xenografted athymic mouse at 80 mg/kg/day, po after 14 days | Homo sapiens | 1 | ALA1141628 | organism-based format | Scientific Literature | |
| 19. | ALA935259 | F | Antitumor activity against human L2987 cells xenografted athymic mouse at 107 mg/kg/day, po after 14 days | Homo sapiens | 1 | ALA1141628 | organism-based format | Scientific Literature |
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