| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA947997 | B | Inhibition of human SGLT2 expressed in CHO cells assessed as inhibition of [14C]AMG accumulation | Homo sapiens | 5 | ALA1142359 | cell-based format | Scientific Literature | |
| 2. | ALA947998 | B | Inhibition of human SGLT1 expressed in CHO cells assessed as inhibition of [14C]AMG accumulation | Homo sapiens | 5 | ALA1142359 | cell-based format | Scientific Literature | |
| 3. | ALA947999 | B | Selectivity for human SGLT2 over human SGLT1 | Homo sapiens | 5 | ALA1142359 | assay format | Scientific Literature | |
| 4. | ALA948000 | B | Inhibition of rat SGLT2 expressed in CHO cells assessed as inhibition of [14C]AMG accumulation | Rattus norvegicus | 1 | ALA1142359 | cell-based format | Scientific Literature | |
| 5. | ALA948001 | B | Selectivity for rat SGLT2 over rat SGLT1 | Rattus norvegicus | 1 | ALA1142359 | assay format | Scientific Literature | |
| 6. | ALA948002 | B | Inhibition of human GLUT1-mediated 2-deoxyglucose uptake in human adipocytes at 20 uM | Homo sapiens | 1 | ALA1142359 | cell-based format | Scientific Literature | |
| 7. | ALA948003 | B | Inhibition of human GLUT4-mediated 2-deoxyglucose uptake in human adipocytes at 20 uM | Homo sapiens | 1 | ALA1142359 | cell-based format | Scientific Literature | |
| 8. | ALA948004 | F | Induction of glucosuria in po dosed Sprague-Dawley rat after 24 hrs | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature | |
| 9. | ALA948005 | F | Induction of glucosuria in Sprague-Dawley rat assessed as glucose loss per 200 gm of body weight at 0.1 mg/kg after 24 hrs | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature | |
| 10. | ALA948006 | F | Induction of glucosuria in Sprague-Dawley rat assessed as glucose loss per 200 gm of body weight at 1.0 mg/kg after 24 hrs | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature | |
| 11. | ALA948007 | F | Reduction in blood glucose levels in streptozotocin-induced diabetic Sprague-Dawley rat at 0.1 mg/kg, po after 5 hrs | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature | |
| 12. | ALA948008 | F | Reduction in blood glucose levels in streptozotocin-induced diabetic Sprague-Dawley rat at 0.01 mg/kg, po after 5 hrs | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature | |
| 13. | ALA948009 | F | Reduction in blood glucose levels in streptozotocin-induced diabetic Sprague-Dawley rat at 0.03 mg/kg, po after 5 hrs | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature | |
| 14. | ALA948010 | A | Fraction unbound in rat serum at 10 uM | Rattus norvegicus | 1 | ALA1142359 | cell-free format | Scientific Literature | |
| 15. | ALA948011 | A | Fraction unbound in human serum at 10 uM | Homo sapiens | 1 | ALA1142359 | cell-free format | Scientific Literature | |
| 16. | ALA948948 | A | Permeability across human Caco-2 cells | Homo sapiens | 1 | ALA1142359 | cell-based format | Scientific Literature | |
| 17. | ALA948949 | A | Oral bioavailability in rat | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature | |
| 18. | ALA948950 | A | Volume of distribution at steady state in rat | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature | |
| 19. | ALA948951 | A | Cmax in rat at 1 mg/kg, po after 1.7 hrs | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature | |
| 20. | ALA948952 | A | Clearance in rat at 1 mg/kg, po after 1.7 hrs | Rattus norvegicus | 1 | ALA1142359 | organism-based format | Scientific Literature |
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