# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA948149 | B | Binding affinity to human recombinant Abl by cell free assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
2. | ALA948150 | F | Antiproliferative activity against human K562 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
3. | ALA948151 | F | Antiproliferative activity against human MEG01 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
4. | ALA2073049 | B | Inhibition of c-Src | Homo sapiens | 8 | single protein format | Scientific Literature | ||
5. | ALA2073050 | B | Inhibition of Abl | Homo sapiens | 10 | single protein format | Scientific Literature | ||
6. | ALA2073052 | F | Antiangiogenic activity in HUVEC co-cultured with vascular smooth muscle cells assessed as inhibition of network formation at 1.8 to 16 uM after 72 hrs | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA2073056 | A | Cytotoxicity against HUVEC co-cultured with vascular smooth muscle cells assessed as rounded-up, unconnected and unicellular morphology phenotype | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
8. | ALA2073059 | B | Inhibition of VEGFR2 expressed in porcine aortic endothelial cells | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
9. | ALA2073060 | P | Aqueous solubility of the compound | 2 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA2073061 | A | Apparent permeability of the compound assessed as membrane permeation by PAMPA | 2 | assay format | Scientific Literature | |||
11. | ALA2073062 | A | Permeability of the compound assessed as membrane retention by PAMPA | 2 | assay format | Scientific Literature | |||
12. | ALA2073063 | A | Metabolic stability of the compound in human liver microsomes assessed as compound remaining | Homo sapiens | 2 | microsome format | Scientific Literature | ||
13. | ALA2073064 | A | Metabolic stability of the compound in human liver microsomes assessed as metabolite M1 formation | Homo sapiens | 2 | microsome format | Scientific Literature | ||
14. | ALA2073066 | A | Metabolic stability of the compound in human liver microsomes assessed as metabolite M3 formation | Homo sapiens | 2 | microsome format | Scientific Literature | ||
15. | ALA2073067 | A | Toxicity in embryos of zebrafish assessed as induction of growth malformation at 0.5 to 2 uM treated 16 hrs post fertilization measured after 24 hrs | Danio rerio | 2 | organism-based format | Scientific Literature | ||
16. | ALA2073069 | B | Inhibition of HER-1 at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
17. | ALA2073070 | B | Inhibition of VEGFR-2 at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
18. | ALA2073071 | B | Inhibition of Flt-3 at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
19. | ALA2073072 | B | Inhibition of IGF-1R at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature | ||
20. | ALA2073073 | B | Inhibition of c-Abl at 10 uM | Homo sapiens | 1 | single protein format | Scientific Literature |