# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA948149 | B | Binding affinity to human recombinant Abl by cell free assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
2. | ALA948150 | F | Antiproliferative activity against human K562 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
3. | ALA948151 | F | Antiproliferative activity against human MEG01 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
4. | ALA2399894 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 100 uM after 60 mins by LC-UV-MS analysis | Homo sapiens | 27 | microsome format | Scientific Literature | ||
5. | ALA2399895 | P | Solubility of the compound in water at 1 mg at 20 degC after 24 to 36 hrs by LC-UV-MS analysis | 27 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA2399896 | A | Apparent permeability of the compound after 5 hrs by PAMPA | 27 | assay format | Scientific Literature | |||
7. | ALA2399897 | F | Cytotoxicity against imatinib-resistant mouse 32D cells expressing Bcr-Abl T315I mutant assessed as growth inhibition after 48 hrs by nucleoCounter analysis | Mus musculus | 27 | cell-based format | Scientific Literature | ||
8. | ALA2399909 | A | Cytotoxicity against mouse 32D cells assessed as growth inhibition after 48 hrs by nucleoCounter analysis | Mus musculus | 27 | cell-based format | Scientific Literature | ||
9. | ALA2399910 | F | Cytotoxicity against imatinib-sensitive mouse 32D cells expressing P210 assessed as growth inhibition after 48 hrs by nucleoCounter analysis | Mus musculus | 27 | cell-based format | Scientific Literature | ||
10. | ALA2399911 | B | Binding affinity to recombinant human c-Src using KVEKIGEGTYGVVYK as substrate | Homo sapiens | 27 | single protein format | Scientific Literature | ||
11. | ALA2399912 | B | Binding affinity to recombinant human Abl T315I mutant using abitide as substrate | Homo sapiens | 27 | assay format | Scientific Literature | ||
12. | ALA2399913 | B | Binding affinity to recombinant wild type human Abl using abitide as substrate | Homo sapiens | 27 | single protein format | Scientific Literature |