# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA948149 | B | Binding affinity to human recombinant Abl by cell free assay | Homo sapiens | 13 | single protein format | Scientific Literature | ||
2. | ALA948150 | F | Antiproliferative activity against human K562 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
3. | ALA948151 | F | Antiproliferative activity against human MEG01 cells | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
4. | ALA1775364 | A | Apparent permeability of the compound at pH 7.4 by PAMPA assay | 9 | assay format | Scientific Literature | |||
5. | ALA1775365 | P | Solubility of the compound in water at pH 7.4 | 9 | small-molecule physicochemical format | Scientific Literature | |||
6. | ALA1775366 | A | Metabolic stability in human liver microsomes assessed as parent compound remaining after 60 mins by LC-MS analysis | Homo sapiens | 9 | microsome format | Scientific Literature | ||
7. | ALA1775368 | A | Metabolic stability in human liver microsomes assessed as metabolite level M3b level after 60 mins by LC-MS analysis | Homo sapiens | 6 | microsome format | Scientific Literature | ||
8. | ALA1775420 | A | Metabolic stability in human liver microsomes assessed as 1-(2-chloro-2-(4-fluorophenyl)ethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine metabolite level after 60 mins by LC-MS analysis | Homo sapiens | 1 | microsome format | Scientific Literature |