# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA975725 | B | Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation at 50 ug/mL after 60 mins by scintillation counting | Rattus norvegicus | 3 | ALA1141812 | single protein format | Scientific Literature | |
2. | ALA975726 | B | Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation at 10 ug/mL after 60 mins by scintillation counting | Rattus norvegicus | 3 | ALA1141812 | single protein format | Scientific Literature | |
3. | ALA975727 | B | Inhibition of rat DNA polymerase beta assessed as [3H]TTP incorporation after 60 mins by scintillation counting in presence of bovine serum albumin | Rattus norvegicus | 3 | ALA1141812 | single protein format | Scientific Literature | |
4. | ALA4138488 | B | Inhibition of full-length GST-fused human CBS using cysteine/homocysteine as substrate assessed as decrease in H2S production preincubated for 3 mins in presence of homocysteine and lead nitrate followed by cysteine addition | Homo sapiens | 12 | ALA4138050 | single protein format | Scientific Literature | |
5. | ALA4138490 | B | Selectivity ratio of IC50 for N-terminal His-tagged CSE extracted from human HepG2 cells expressed in Escherichia coli BL21 (DE3) using cysteine as substrate assessed as decrease in H2S production to IC50 for full-length GST-fused human CBS using cysteine/homocysteine as substrate assessed as decrease in H2S production | Homo sapiens | 3 | ALA4138050 | assay format | Scientific Literature | |
6. | ALA4138491 | B | Reversible inhibition of full-length GST-fused human CBS using cysteine/homocysteine as substrate assessed as decrease in H2S production at 100 uM preincubated for 1 hr followed by ultrafiltration for 5 times | Homo sapiens | 11 | ALA4138050 | single protein format | Scientific Literature |