| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA651190 | B | Selectivity as the ratio of Ki of beta-2 adrenergic receptor to the Ki of beta-3 adrenergic receptor. | 38 | protein format | Scientific Literature | |||
| 2. | ALA652585 | B | Binding affinity against CHO cells transfected with human beta-3 adrenergic receptor in the presence of [125I]iodocyanopindolol | 38 | cell-based format | Scientific Literature | |||
| 3. | ALA652586 | F | Human beta-3 adrenergic receptor agonist activity by measurement of cAMP accumulation levels in CHO membranes expressing human beta-3 receptor. | 37 | cell membrane format | Scientific Literature | |||
| 4. | ALA654262 | B | Selectivity measured as the ratio of Ki of Beta-1 Adrenergic receptor to the Ki of Beta-3 Adrenergic receptor | 38 | protein format | Scientific Literature | |||
| 5. | ALA819027 | F | Dissociation constant against a series of agonists of membranes of the turkey erythrocyte containing mainly beta-adrenoceptors was determined. | Meleagris gallopavo | 9 | assay format | Scientific Literature | ||
| 6. | ALA3280902 | B | Agonist activity at beta-2 adrenergic receptor in guinea pig tracheal chain assessed as relaxation of spontaneously contracted tracheal smooth muscle | Cavia porcellus | 14 | single protein format | Scientific Literature | ||
| 7. | ALA3280903 | B | Agonist activity at beta-1 adrenergic receptor in guinea pig right atria assessed as increase in contraction rate of spontaneously beating right atria | Cavia porcellus | 12 | single protein format | Scientific Literature | ||
| 8. | ALA3280905 | B | Intrinsic activity at beta-1 adrenergic receptor in guinea pig right atria assessed as increase in contraction rate of spontaneously beating right atria relative to isoproterenol | Cavia porcellus | 10 | single protein format | Scientific Literature | ||
| 9. | ALA3280906 | B | Selectivity ratio of ED25 for beta-1 adrenergic receptor in guinea pig right atria to ED50 for beta-2 adrenergic receptor in guinea pig tracheal chain | Cavia porcellus | 12 | assay format | Scientific Literature | ||
| 10. | ALA3280907 | B | Intrinsic activity at beta-2 adrenergic receptor in guinea pig tracheal chain assessed as relaxation of spontaneously contracted tracheal smooth muscle relative to papaverine | Cavia porcellus | 12 | single protein format | Scientific Literature | ||
| 11. | ALA3282835 | F | Analgesic activity in sc dosed mouse assessed as reduction in phenylalanine-induced writhing | Mus musculus | 18 | organism-based format | Scientific Literature | ||
| 12. | ALA3282836 | F | Analgesic activity in sc dosed rat by tail flick test | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
| 13. | ALA3282839 | F | Inhibition of reserpine-induced ptosis in po dosed mouse | Mus musculus | 15 | organism-based format | Scientific Literature | ||
| 14. | ALA3282840 | F | Reversal of reserpine-induced ptosis in po dosed mouse | Mus musculus | 15 | organism-based format | Scientific Literature | ||
| 15. | ALA3282843 | P | Partition coefficient, log P of the compound in CHCl3-H2O system at 4 ug/ml at pH 7.4 | 7 | small-molecule physicochemical format | Scientific Literature | |||
| 16. | ALA3283077 | F | Antagonism of morphine-induced analgesia in rat at 20 mg/kg, sc | Rattus norvegicus | 13 | organism-based format | Scientific Literature | ||
| 17. | ALA4651403 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 4,309 | organism-based format | IMI-CARE SARS-CoV-2 Data |
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