# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1006951 | F | Antimicrobial activity Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method | Cutibacterium acnes | 79 | ALA1149024 | organism-based format | Scientific Literature | |
2. | ALA3095432 | B | Inhibition of human COX2 using arachidonic acid as substrate assessed as formation of TMPD at 50 uM incubated for 5 mins prior to substrate addition measured after 5 mins by spectrophotometry | Homo sapiens | 16 | ALA3091418 | single protein format | Scientific Literature | |
3. | ALA3095433 | B | Inhibition of human 5-LOX using lionleic acid as substrate assessed as formation of 13-HPOD at 50 uM incubated for 10 mins prior to substrate addition measured after 10 secs by UV absorbance assay | Homo sapiens | 8 | ALA3091418 | single protein format | Scientific Literature | |
4. | ALA3738193 | B | Inhibition of recombinant N-terminal His6-tagged KAT8 (unknown origin) expressed in Escherichia Coli BL21 DE3 cells assessed as reduction of Co A level using histone H4 substrate at 400 uM after 15 mins by CPM fluorescence assay | Homo sapiens | 10 | ALA3734689 | cell-based format | Scientific Literature | |
5. | ALA3738205 | B | Inhibition of recombinant N-terminal His6-tagged KAT8 (unknown origin) expressed in Escherichia Coli BL21 DE3 cells assessed as reduction of Co A level using histone H4 substrate after 15 mins by CPM fluorescence assay | Homo sapiens | 10 | ALA3734689 | cell-based format | Scientific Literature | |
6. | ALA3738206 | B | Inhibition of human recombinant Histone acetyltransferase p300 catalytic domain (1284-1672 residues) using [3H]Acetyl-CoA and histone H3 substrate at 50 uM after 1 hr by liquid scintillation counting | Homo sapiens | 10 | ALA3734689 | single protein format | Scientific Literature | |
7. | ALA3738207 | B | Inhibition of human recombinant Histone acetyltransferase p300 catalytic domain (1284-1672 residues) using [3H]Acetyl-CoA and histone H3 substrate at 200 uM after 1 hr by liquid scintillation counting | Homo sapiens | 5 | ALA3734689 | single protein format | Scientific Literature |