# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA989425 | F | Antimicrobial activity against Enterococcus faecalis by broth microdilution susceptibility assay | Enterococcus faecalis | 1 | ALA1146567 | organism-based format | Scientific Literature | |
2. | ALA989426 | F | Antimicrobial activity against Micrococcus luteus by broth microdilution susceptibility assay | Micrococcus luteus | 1 | ALA1146567 | organism-based format | Scientific Literature | |
3. | ALA989427 | F | Cytotoxicity against mouse P388 cells | Mus musculus | 7 | ALA1146567 | cell-based format | Scientific Literature | |
4. | ALA2065750 | B | Inhibition of Clostridium botulinum Hall BoNT/A protease activity using Ac-SNKTRIDEANQRATKML-NH2 as substrate at 100 uM after 5 mins by RP-HPLC analysis | Clostridium botulinum | 6 | ALA2062470 | single protein format | Scientific Literature | |
5. | ALA2065751 | B | Inhibition of Clostridium botulinum Hall BoNT/A protease activity using Ac-SNKTRIDEANQRATKML-NH2 as substrate at 20 uM after 5 mins by RP-HPLC analysis | Clostridium botulinum | 6 | ALA2062470 | single protein format | Scientific Literature | |
6. | ALA2065752 | B | Inhibition of Clostridium botulinum Hall BoNT/A protease activity using Ac-SNKTRIDEANQRATKML-NH2 as substrate after 5 mins by RP-HPLC analysis | Clostridium botulinum | 6 | ALA2062470 | single protein format | Scientific Literature | |
7. | ALA2065753 | B | Inhibition of Clostridium botulinum Hall BoNT/A-mediated paralysis in CD1 mouse phrenic nerve hemidiaphragm assessed as time required to 50% loss of twitch tension at 20 uM measured upto 5 hrs (Rvb = 62 mins) | Clostridium botulinum | 6 | ALA2062470 | single protein format | Scientific Literature | |
8. | ALA2065754 | B | Inhibition of Clostridium botulinum Hall BoNT/A-mediated paralysis in CD1 mouse phrenic nerve hemidiaphragm assessed as time required to 50% loss of twitch tension at 2 uM measured upto 5 hrs (Rvb = 62 mins) | Clostridium botulinum | 6 | ALA2062470 | single protein format | Scientific Literature | |
9. | ALA3874884 | F | Antimicrobial activity against Staphylococcus aureus | Staphylococcus aureus | 16 | ALA3872273 | assay format | Scientific Literature | |
10. | ALA3874885 | F | Antimicrobial activity against Escherichia coli | Escherichia coli | 16 | ALA3872273 | assay format | Scientific Literature | |
11. | ALA3874886 | F | Antimicrobial activity against Mycobacterium smegmatis | Mycolicibacterium smegmatis | 16 | ALA3872273 | assay format | Scientific Literature | |
12. | ALA3874887 | F | Antimicrobial activity against Candida albicans | Candida albicans | 16 | ALA3872273 | assay format | Scientific Literature | |
13. | ALA3874888 | F | Antimicrobial activity against Aspergillus niger | Aspergillus niger | 16 | ALA3872273 | assay format | Scientific Literature | |
14. | ALA3874889 | B | Inhibition of Salmonella typhimurium Peptidyl-tRNA hydrolase assessed as reduction in peptidyl-tRNA cleavage to free tRNA by gel electrophoresis | Salmonella enterica subsp. enterica serovar Typhimurium | 7 | ALA3872273 | assay format | Scientific Literature | |
15. | ALA3874890 | B | Inhibition of Escherichia coli Peptidyl-tRNA hydrolase assessed as reduction in peptidyl-tRNA cleavage to free tRNA by gel electrophoresis | Escherichia coli | 7 | ALA3872273 | assay format | Scientific Literature | |
16. | ALA3874891 | B | Inhibition of Pseudomonas aeruginosa Peptidyl-tRNA hydrolase assessed as reduction in peptidyl-tRNA cleavage to free tRNA by gel electrophoresis | Pseudomonas aeruginosa | 7 | ALA3872273 | assay format | Scientific Literature | |
17. | ALA5054466 | B | Inhibition of topoisomerase 1 (unknown origin) assessed as relaxation of supercoiled plasmid pUC18 measured after 30 mins by ethidium bromide staining based agarose gel electrophoresis | Homo sapiens | 3 | ALA5053515 | single protein format | Scientific Literature | |
18. | ALA5054467 | B | Inhibition of human topoisomerase 2a assessed as reduction in decatenation of kinetoplast DNA at 25 uM using kinetoplast DNA as substrate incubated for 2 hrs by ethidium bromide staining based agarose gel electrophoresis method relative to control | Homo sapiens | 3 | ALA5053515 | single protein format | Scientific Literature | |
19. | ALA5054469 | F | Cytotoxicity against human HepG2 cells assessed as reduction in cell viability measured at 48 hrs by resazurin reagent based assay | Homo sapiens | 5 | ALA5053515 | cell-based format | Scientific Literature | |
20. | ALA5054471 | F | Cytotoxicity against human CCF-STTG1 cells assessed as reduction in cell viability measured at 48 hrs by resazurin reagent based assay | Homo sapiens | 6 | ALA5053515 | cell-based format | Scientific Literature |