# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA616082 | B | Binding affinity towards 5-hydroxytryptamine 1A receptor by the displacement of [125I]trans-8-OH-PIPAT in membrane homogenates of hippocampal tissue of rat brain | Rattus norvegicus | 10 | ALA1126858 | tissue-based format | Scientific Literature | |
2. | ALA618310 | A | Unbound fraction (plasma) | Homo sapiens | 120 | ALA1148291 | cell-free format | Scientific Literature | |
3. | ALA624569 | A | Observed volume of distribution | Homo sapiens | 120 | ALA1148291 | organism-based format | Scientific Literature | |
4. | ALA631962 | P | Aqueous solubility | 148 | ALA1132890 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA631377 | P | Partition coefficient (logD7.4) | 90 | ALA1134540 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA633649 | A | Delta logD (logD6.5 - logD7.4) | 111 | ALA1133765 | assay format | Scientific Literature | ||
7. | ALA635199 | P | Partition coefficient (logP) | 16 | ALA1121439 | small-molecule physicochemical format | Scientific Literature | ||
8. | ALA633438 | A | Tested for antimuscarinic potency on guinea pig heart force | Cavia porcellus | 5 | ALA1124194 | organism-based format | Scientific Literature | |
9. | ALA633439 | A | Tested for antimuscarinic potency on guinea pig heart rate | Cavia porcellus | 5 | ALA1124194 | organism-based format | Scientific Literature | |
10. | ALA633440 | A | Tested for antimuscarinic potency on guinea pig ileum | Cavia porcellus | 5 | ALA1124194 | organism-based format | Scientific Literature | |
11. | ALA633441 | A | Tested for antimuscarinic potency on rat bladder | Rattus norvegicus | 5 | ALA1124194 | organism-based format | Scientific Literature | |
12. | ALA639590 | A | Tested for the dissociation constant of the compound | 9 | ALA1121439 | assay format | Scientific Literature | ||
13. | ALA634283 | P | Partition coefficient (logD6.5) | 114 | ALA1133765 | small-molecule physicochemical format | Scientific Literature | ||
14. | ALA632541 | P | pKa value was determined | 10 | ALA1124864 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA633292 | P | Ionization constant (pKa) | 80 | ALA1148291 | small-molecule physicochemical format | Scientific Literature | ||
16. | ALA639967 | T | Acute toxicity in mice | Mus musculus | 8 | ALA1122860 | organism-based format | Scientific Literature | |
17. | ALA639853 | A | Fraction ionized (pH 7.4) | 64 | ALA1135488 | assay format | Scientific Literature | ||
18. | ALA639855 | A | Unbound fraction (plasma) | 64 | ALA1135488 | cell-free format | Scientific Literature | ||
19. | ALA638828 | A | Unbound fraction (tissues) | 64 | ALA1135488 | assay format | Scientific Literature | ||
20. | ALA641100 | P | Ionisation constant (pKa) | 38 | ALA1135488 | small-molecule physicochemical format | Scientific Literature |