| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA1794536 | F | PUBCHEM_BIOASSAY: qHTS for Inhibitors of Polymerase Kappa. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID588638] | 7,413 | assay format | PubChem BioAssays | |||
| 2. | ALA2020504 | B | Inhibition of recombinant SIRT2 assessed as lysine deacetylation at 25 uM relative to control | 5 | single protein format | Scientific Literature | |||
| 3. | ALA968379 | B | Inhibition of adenosine A3 receptor | 1 | single protein format | Scientific Literature | |||
| 4. | ALA968380 | P | Lipophilicity, log P of the compound | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 5. | ALA968381 | A | Drug level in mouse cerebral cortex at 50 mg/kg, po administered for 5 days after 5 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA968382 | A | Plasma half life in po dosed mouse | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA968383 | A | Half life in po dosed mouse brain | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA968384 | A | Drug concentration in mouse brain at 10 mg/kg, po after 16 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA968385 | A | Drug concentration in mouse plasma at 25 mg/kg, po after 24 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA968386 | T | Toxicity in R6/2 mouse assessed as effect on body weight at 50 mg/kg/12 hrs for 4 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA968387 | T | Toxicity in R6/2 mouse assessed as effect on body weight at 100 mg/kg/12 hrs for 4 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA968388 | T | Toxicity in R6/2 mouse assessed as body weight at 200 mg/kg/12 hrs for 4 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA968389 | T | Toxicity in R6/2 mouse assessed as survival at 100 mg/kg/12 hrs for 4 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA968390 | T | Toxicity in R6/2 mouse assessed as survival at 200 mg/kg/12 hrs for 4 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA968391 | B | Inhibition of DAT | 1 | single protein format | Scientific Literature | |||
| 16. | ALA968392 | F | Reduction of decrease in motor dysfunction in R6/2 mouse assessed as increase in latency to fall at 8 weeks of age by rotarod test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA968393 | F | Reduction of decrease in motor dysfunction in R6/2 mouse assessed as increase in latency to fall at 11 weeks of age by rotarod test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA968394 | F | Reduction of decrease in motor dysfunction in R6/2 mouse assessed as improvement in wire-hang endurance at 100 mg/kg/12 hrs after 12.5 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 19. | ALA968395 | A | Reduction of decrease in motor dysfunction in R6/2 mouse assessed as improvement in wire-hang endurance after 9.5 weeks | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA968396 | F | Decrease in neuronal atrophy in R6/2 mouse assessed as brain weight | Mus musculus | 1 | organism-based format | Scientific Literature |
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