# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3436042 | Functional | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGLUT1 that are glucose transport deficient and complemented with the human glucose transporter GLUT1. Activity is measured by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | ALA3433997 | assay format | St Jude Leishmania Screening | |
2. | ALA3436043 | Functional | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmPfHT that are glucose transport deficient and complemented with the Plasmodium falciparum hexose transporter. Activity is measured by by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | ALA3433997 | assay format | St Jude Leishmania Screening | |
3. | ALA3436044 | Functional | ST_JUDE_LEISH: Cytotoxicity at 2uM final concentration against transgenic Leishmania Mexicana promastigotes LmGT2 that are glucose transport deficient and complemented with the L. Mexicana glucose transporter 2. Activity is measured by by DNA content using SYBR green in vitro | Leishmania mexicana | 13,179 | ALA3433997 | assay format | St Jude Leishmania Screening | |
4. | ALA3562145 | Functional | PubChem BioAssay. Biochemical screen of P. falciparum CDPK4. (Class of assay: confirmatory) | 55 | ALA1201862 | assay format | PubChem BioAssays | ||
5. | ALA3767620 | Binding | Inhibition of c-Met (unknown origin) | Homo sapiens | 13 | ALA3763130 | single protein format | Scientific Literature | |
6. | ALA1826482 | Binding | Inhibition of human recombinant c-MET kinase expressed in A549 cells assessed as inhibition of HGF-induced autophosphorylation by ELISA method | Homo sapiens | 42 | ALA1821723 | cell-based format | Scientific Literature | |
7. | ALA1826483 | Binding | Inhibition of human recombinant c-MET kinase in GTL-16 cells assessed as inhibition of HGF-induced proliferation by sandwich ELISA method | Homo sapiens | 1 | ALA1821723 | cell-based format | Scientific Literature | |
8. | ALA1825351 | Physicochemical | Lipophilicity, log D of the compound at pH 7.4 | 2 | ALA1821723 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA1908399 | Binding | Binding constant for BRSK1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
10. | ALA1908400 | Binding | Binding constant for MAPKAPK2 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
11. | ALA1908401 | Binding | Binding constant for NEK9 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
12. | ALA1908402 | Binding | Binding constant for MYLK2 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
13. | ALA1908403 | Binding | Binding constant for MLK1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
14. | ALA1908404 | Binding | Binding constant for DCAMKL3 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
15. | ALA1908405 | Binding | Binding constant for CDC2L1 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
16. | ALA1908406 | Binding | Binding constant for MYLK kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
17. | ALA1908407 | Binding | Binding constant for SRMS kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
18. | ALA1908408 | Binding | Binding constant for STK35 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
19. | ALA1908409 | Binding | Binding constant for DYRK1A kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature | ||
20. | ALA1908410 | Binding | Binding constant for ERK2 kinase domain | 72 | ALA1908390 | single protein format | Scientific Literature |