| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3815853 | ADME | Displacement of [3H]RS-79948-197 from recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane by scintillation counting method | Homo sapiens | 17 | ALA3813687 | cell-based format | Scientific Literature | |
| 2. | ALA3815854 | ADME | Agonist activity at recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane incubated for 30 mins by [35S]GTPgammaS binding assay | Homo sapiens | 17 | ALA3813687 | cell-based format | Scientific Literature | |
| 3. | ALA3815855 | ADME | Intrinsic activity at recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane incubated for 30 mins by [35S]GTPgammaS binding assay relative to adrenaline | Homo sapiens | 16 | ALA3813687 | cell-based format | Scientific Literature | |
| 4. | ALA645686 | Binding | Tested for Binding affinity towards alpha-1 adrenergic receptor | Rattus norvegicus | 9 | ALA1133123 | protein format | Scientific Literature | |
| 5. | ALA643713 | Binding | In vitro binding affinity against alpha-2 adrenergic receptor in rat | 35 | ALA1132495 | assay format | Scientific Literature | ||
| 6. | ALA643883 | Binding | in vitro alpha-2A adrenergic receptor binding assay from rats, using RX 821002 as the displaceable ligand | 8 | ALA1133002 | single protein format | Scientific Literature | ||
| 7. | ALA646819 | Binding | In vitro binding affinity against alpha-2D adrenergic receptor of male Wistar rat | Rattus norvegicus | 36 | ALA1134368 | single protein format | Scientific Literature | |
| 8. | ALA646821 | Binding | Binding affinity towards alpha-2D adrenergic receptor | Rattus norvegicus | 9 | ALA1133123 | single protein format | Scientific Literature | |
| 9. | ALA647841 | Binding | In vitro rat alpha-2D adrenergic receptor binding using p-aminoclonidine | Rattus norvegicus | 9 | ALA1133002 | single protein format | Scientific Literature | |
| 10. | ALA716877 | Functional | QT interval was determined during cardiovascular test in normotensive male albino Long-Evans rat | Mus musculus | 1 | ALA1134368 | organism-based format | Scientific Literature | |
| 11. | ALA846310 | Functional | ED50 value was measured using rat air-induced abdominal irritant test(RAIT) | Rattus norvegicus | 5 | ALA1133002 | organism-based format | Scientific Literature | |
| 12. | ALA880402 | Binding | Selectivity ratio of alpha1/alpha2d | Rattus norvegicus | 9 | ALA1133123 | assay format | Scientific Literature | |
| 13. | ALA895079 | Binding | Displacement of [3H]RX 821002 from human adrenergic Alpha-2C receptor expressed in CHO cells | Homo sapiens | 10 | ALA1148710 | cell-based format | Scientific Literature | |
| 14. | ALA895086 | Binding | Displacement of [3H]RX 821002 from human adrenergic alpha-2c receptor expressed in CHO cells in presence of GppNHp/Na | Homo sapiens | 2 | ALA1148710 | cell-based format | Scientific Literature | |
| 15. | ALA1741321 | Functional | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2d6 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
| 16. | ALA1741322 | Functional | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp1a2 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
| 17. | ALA1741323 | Functional | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c19 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
| 18. | ALA1741324 | Functional | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp3a4 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
| 19. | ALA1741325 | Functional | PUBCHEM_BIOASSAY: Cytochrome panel assay with activity outcomes. (Class of assay: other) Panel member name: p450-cyp2c9 Compounds with AC50 equal or less than 10 uM are considered active | 16,572 | ALA1201862 | assay format | PubChem BioAssays | ||
| 20. | ALA1794345 | Functional | PUBCHEM_BIOASSAY: Primary qHTS for delayed death inhibitors of the malarial parasite plastid, 96 hour incubation. (Class of assay: confirmatory) [Related pubchem assays (depositor defined):AID488745, AID488752, AID488774, AID504848, AID504850] | Plasmodium falciparum | 170,142 | ALA1201862 | organism-based format | PubChem BioAssays |
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