| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA953972 | B | Displacement of [3H]CP-55940 from human CB2 receptor | Homo sapiens | 53 | single protein format | Scientific Literature | ||
| 2. | ALA953973 | B | Displacement of [3H]CP-55940 from human CB1 receptor | Homo sapiens | 52 | single protein format | Scientific Literature | ||
| 3. | ALA953974 | F | Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assay | Homo sapiens | 53 | cell-based format | Scientific Literature | ||
| 4. | ALA953975 | F | Agonist activity at cloned human CB2 receptor in Sf9 cells assessed by [35S]GTPgammaS binding assay relative to delta9-THC | Homo sapiens | 43 | cell-based format | Scientific Literature | ||
| 5. | ALA3376221 | B | Agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP at 100 uM by scintillation counting (Rvb = 0 +/- 1%) | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 6. | ALA3376222 | F | Antagonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP at 100 uM by scintillation counting in presence of 30 nM CP55940 (Rvb = 0 +/- 5%) | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 7. | ALA3376224 | B | Agonist activity at human CB2 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scintillation counting | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 8. | ALA3379274 | B | Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP at 100 uM by scintillation counting (Rvb = 0 +/- 3%) | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 9. | ALA3379277 | B | Agonist activity at human CB1 receptor expressed in Sf9 cells coexpressing Galpha i2 assessed as Galpha GTPase activity using [gamma-33P]GTP by scintillation counting | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3379278 | B | Selectivity ratio of EC50 for human CB1 receptor to EC50 for human CB2 receptor | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 11. | ALA4023557 | B | Inhibition of human BChE at 10 uM using BTC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's method relative to control | Homo sapiens | 5 | single protein format | Scientific Literature | ||
| 12. | ALA4023562 | B | Inhibition of human erythrocyte AChE at 100 uM using ATC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's method relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4023567 | B | Displacement of [3H]-CP55950 from human CB2 receptor expressed in HEK cell membranes after 3 hrs by scintillation counting method | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 14. | ALA4023569 | B | Inhibition of electric eel AChE at 100 uM using ATC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's method relative to control | Electrophorus electricus | 6 | single protein format | Scientific Literature | ||
| 15. | ALA4023571 | B | Displacement of [3H]-CP55950 from human CB1 receptor expressed in CHO cell membranes at 10 uM after 3 hrs by scintillation counting method relative to control | Homo sapiens | 16 | cell-based format | Scientific Literature | ||
| 16. | ALA4023573 | B | Inhibition of equine BChE using BTC iodide as substrate preincubated for 4.5 mins followed by substrate addition measured after 2.5 mins by Ellman's method | Equus caballus | 4 | single protein format | Scientific Literature | ||
| 17. | ALA4023575 | A | Cytotoxicity against human U266 cells assessed as decrease in cell viability after 72 hrs by MTT assay | Homo sapiens | 9 | cell-based format | Scientific Literature | ||
| 18. | ALA4023576 | F | Agonist activity at CB2 receptor in human U266 cells assessed as decrease in cAMP accumulation at 50 uM after 2 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 19. | ALA4023577 | F | Agonist activity at CB2 receptor in human U266 cells assessed as decrease in AM630-induced cAMP accumulation at 50 uM after 2 hrs by ELISA | Homo sapiens | 4 | cell-based format | Scientific Literature | ||
| 20. | ALA4023578 | B | Agonist activity at CB2 receptor in human U266 cells assessed as decrease in MIF mRNA expression at 50 uM after 2 hrs by qRT-PCR method | Homo sapiens | 4 | cell-based format | Scientific Literature |
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