| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA946415 | F | Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells by [35S]GTPgammaS binding assay | Homo sapiens | 14 | ALA1157487 | cell-based format | Scientific Literature | |
| 2. | ALA946416 | B | Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells by SPA | Homo sapiens | 14 | ALA1157487 | cell-based format | Scientific Literature | |
| 3. | ALA946417 | F | Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells at 1 uM by [35S]GTPgammaS binding assay | Homo sapiens | 41 | ALA1157487 | cell-based format | Scientific Literature | |
| 4. | ALA946418 | B | Displacement of [125I]CCl22 from human CCR4 receptor expressed in mouse B300-19 cells at 1 uM by SPA | Homo sapiens | 41 | ALA1157487 | cell-based format | Scientific Literature | |
| 5. | ALA946419 | F | Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxis by bioluminescent assay | Homo sapiens | 9 | ALA1157487 | cell-based format | Scientific Literature | |
| 6. | ALA946420 | F | Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxis by bioluminescent assay | Mus musculus | 10 | ALA1157487 | cell-based format | Scientific Literature | |
| 7. | ALA946421 | A | Cytotoxicity against CCR4 expressing mouse B300-19 cells at 3 uM after 12 hrs by alamar blue assay | Mus musculus | 1 | ALA1157487 | cell-based format | Scientific Literature | |
| 8. | ALA980948 | A | Metabolic stability in human liver microsomes assessed as intrinsic clearance | Homo sapiens | 6 | ALA1139410 | microsome format | Scientific Literature | |
| 9. | ALA980949 | F | Antagonist activity at human CCR4 receptor by [35S]GTPgammaS binding assay | Homo sapiens | 12 | ALA1139410 | assay format | Scientific Literature | |
| 10. | ALA980950 | F | Antagonist activity at human CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assay | Homo sapiens | 9 | ALA1139410 | assay format | Scientific Literature | |
| 11. | ALA980951 | F | Antagonist activity at mouse CCR4 receptor assessed as inhibition of CCL22-induced chemotaxis by bioluminescent assay | Mus musculus | 8 | ALA1139410 | assay format | Scientific Literature | |
| 12. | ALA968019 | B | Displacement of [121I]CCL22 from human CCR4 receptor by scintillation proximity assay | Homo sapiens | 12 | ALA1139410 | single protein format | Scientific Literature | |
| 13. | ALA1020783 | F | Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced [35S]GTPgammaS binding | Homo sapiens | 13 | ALA1139358 | cell-based format | Scientific Literature | |
| 14. | ALA1020785 | F | Antagonist activity at human CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxis | Homo sapiens | 20 | ALA1139358 | cell-based format | Scientific Literature | |
| 15. | ALA1020786 | F | Antagonist activity at mouse CCR4 receptor expressed in mouse B300-19 cells assessed as CCL22-induced chemotaxis | Mus musculus | 20 | ALA1139358 | cell-based format | Scientific Literature | |
| 16. | ALA1020787 | A | Intrinsic clearance in human liver microsomes | Homo sapiens | 5 | ALA1139358 | microsome format | Scientific Literature | |
| 17. | ALA1020788 | F | Antiinflammatory activity against oxazolone-induced contact hypersensitivity in BALB/c mouse model of acute dermatitis assessed as inhibition of ear swelling at 30 mg/kg, sc qd | Mus musculus | 2 | ALA1139358 | organism-based format | Scientific Literature | |
| 18. | ALA1020789 | F | Antiinflammatory activity against oxazolone-induced contact hypersensitivity in BALB/c mouse model of acute dermatitis assessed as inhibition of ear swelling at 100 mg/kg, po bid | Mus musculus | 1 | ALA1139358 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!