| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA976298 | B | Inhibition of human wild type CFTR expressed in rat FRT cells assessed as chloride current by short-circuit current measurements | Homo sapiens | 57 | cell-based format | Scientific Literature | ||
| 2. | ALA4495582 | F | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | assay format | SARS-CoV-2 Screening Data 2020-21 | ||
| 3. | ALA4513082 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | ||
| 4. | ALA4628078 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophage cells at 10 uM in presence of mono sodium urate relative to control | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 5. | ALA4628079 | B | Inhibition of CFTR in human HT-29 cells assessed as effect on intracellular chloride efflux at 20 uM relative to control | Homo sapiens | 21 | cell-based format | Scientific Literature | ||
| 6. | ALA4628081 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophage cells assessed as effect on IL-1beta production in presence of nigericin by ELISA | Homo sapiens | 21 | assay format | Scientific Literature | ||
| 7. | ALA4628082 | A | Half life in human liver microsomes in presence of NADPH | Homo sapiens | 11 | microsome format | Scientific Literature | ||
| 8. | ALA4628083 | A | Clearance in human liver microsomes in presence of NADPH | Homo sapiens | 11 | microsome format | Scientific Literature | ||
| 9. | ALA4628084 | A | Half life in mouse liver microsomes in presence of NADPH | Mus musculus | 11 | microsome format | Scientific Literature | ||
| 10. | ALA4628085 | A | Clearance in mouse liver microsomes in presence of NADPH | Mus musculus | 11 | microsome format | Scientific Literature | ||
| 11. | ALA4628086 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophages assessed as inhibition of IL-1beta secretion at 5 uM in presence of nigericin by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA4628087 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophages assessed as inhibition of IL-1beta secretion at 5 uM in presence of ATP by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 13. | ALA4628088 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophages assessed as inhibition of IL-1beta secretion at 5 uM in presence of mono sodium urate by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 14. | ALA4628089 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophages assessed as inhibition of IL-1beta secretion in presence of nigericin by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 15. | ALA4628090 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophages assessed as inhibition of IL-1beta secretion in presence of ATP by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 16. | ALA4628091 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in LPS-primed bone marrow derived macrophages assessed as inhibition of IL-1beta secretion in presence of mono sodium urate by ELSIA | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 17. | ALA4628092 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in bone marrow derived macrophage cells assessed as effect on nigericin-induced TNF-alpha secretion at 5 uM by ELISA | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 18. | ALA4628093 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in bone marrow derived macrophage cells assessed as effect on ATP-induced TNF-alpha secretion at 5 uM by ELISA | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA4628094 | B | Inhibition of NLRP3 inflammasome (unknown origin) activation in bone marrow derived macrophage cells assessed as effect on mono sodium urate-induced TNF-alpha secretion at 5 uM by ELISA | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 20. | ALA4628095 | B | Inhibition of NLRC4 inflammasome (unknown origin) activation in bone marrow derived macrophages assessed as inhibition of Salmonella-induced IL-1beta secretion at 5 uM by ELISA | Homo sapiens | 1 | single protein format | Scientific Literature |
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