| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA977358 | B | Inhibition of human recombinant cathepsin K by fluorescence assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 2. | ALA977359 | B | Inhibition of human recombinant cathepsin L by fluorescence assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 3. | ALA980012 | B | Inhibition of human recombinant cathepsin S by fluorescence assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 4. | ALA980014 | A | Half life in Sprague-Dawley rat at 1 mg/mL/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 5. | ALA980016 | A | Plasma clearance in Sprague-Dawley rat at 1 mg/mL/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA980018 | A | Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/mL/kg, iv | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA980874 | A | Bioavailability in Sprague-Dawley rat at 3 mg/5 mL/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA980875 | F | Antibone resorptive activity in Sprague-Dawley rat assessed as inhibition of cathepsin K-mediated C-terminal telopeptidase of type 1 collagen degradation at 100 mg/kg/day, po for 11 days measured on 24 hrs after final administration by RatLaps ELISA | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 9. | ALA980876 | A | Drug level in Sprague-Dawley rat serum at 100 mg/kg/day, po for 11 days measured on 25 hrs after final administration | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 10. | ALA980877 | A | Drug level in Sprague-Dawley rat bone marrow at 100 mg/kg/day, po for 11 days measured on 25 hrs after final administration | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 11. | ALA980878 | A | Ratio of drug level in bone marrow to serum in po dosed Sprague-Dawley rat | Rattus norvegicus | 7 | organism-based format | Scientific Literature | ||
| 12. | ALA980886 | B | Inhibition of rat recombinant cathepsin K expressed in Sf21 cells by fluorescence assay | Rattus norvegicus | 8 | cell-based format | Scientific Literature |
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