# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA623156 | A | In vitro metabolic stability in rat hepatocytes | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
2. | ALA623061 | A | Oral bioavailability in rat | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
3. | ALA624143 | P | Calculated partition coefficient (clogP) | 3 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA653656 | F | Percent inhibition of protein concentration in bronchoalveolar lavage fluid (BALF) from actively sensitized Brown norway rats at 2 mg/kg | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
5. | ALA653657 | F | In vivo inhibition of antigen induced eosinophil recruitment in Brown-Norvway Rats at 10 mg/kg peroral dose (non-significant) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
6. | ALA680980 | F | Emetic effect in fasted ferrets at 10 mg/kg peroral dose (n=2 not tested) | Mustela putorius furo | 1 | organism-based format | Scientific Literature | ||
7. | ALA680983 | F | Emetic effect in fasted ferrets at 3 mg/kg peroral dose (n=2 not tested) | Mustela putorius furo | 1 | organism-based format | Scientific Literature | ||
8. | ALA680626 | F | Emetic effect in fasted ferrets at 30 mg/kg peroral dose (n=2 not tested) | Mustela putorius furo | 1 | organism-based format | Scientific Literature | ||
9. | ALA682878 | F | PDE4-related emetic activity in ferrets after intravenous administration at 10 mg/kg | Mustela putorius furo | 5 | organism-based format | Scientific Literature | ||
10. | ALA683458 | F | Antigen-induced bronchoconstriction in guinea pigs after iv administration 10 min pre-treatment | Cavia porcellus | 6 | organism-based format | Scientific Literature | ||
11. | ALA688104 | F | Inhibition of SRS-A-mediated bronchoconstriction and airway microvascular leakage in sensitized guinea pigs at 0.15 mg/kg 1 hr after oral dose | Cavia porcellus | 4 | organism-based format | Scientific Literature | ||
12. | ALA688259 | F | Percent inhibition of eosinophil infiltration in the guinea pig at 30 uM/kg (ip) | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
13. | ALA688111 | F | Inhibition of SRS-A-mediated bronchoconstriction and airway microvascular leakage in sensitized guinea pigs at 0.15 mg/kg peroral dose 1 hr prio to challenge | Cavia porcellus | 3 | organism-based format | Scientific Literature | ||
14. | ALA687455 | F | In vivo inhibition of slow reacting substance of anaphylaxis (SRS-A) mediated bronchoconstriction in guinea pig | Cavia porcellus | 2 | organism-based format | Scientific Literature | ||
15. | ALA697606 | F | Ability to block the release of TNF-alpha in human monocytes | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
16. | ALA702335 | F | Ability to block the release of TNF-alpha in human whole blood | Homo sapiens | 6 | organism-based format | Scientific Literature | ||
17. | ALA701223 | F | Inhibition of TNF-alpha production in human whole blood | Homo sapiens | 3 | organism-based format | Scientific Literature | ||
18. | ALA701919 | F | Inhibition of LPS-induced TNF-alpha production in human whole blood | Homo sapiens | 5 | organism-based format | Scientific Literature | ||
19. | ALA702088 | F | Inhibitory concentration of compound against LPS- induced TNF-alpha production in whole human blood assay | Homo sapiens | 24 | tissue-based format | Scientific Literature | ||
20. | ALA701318 | F | Inhibition of LPS-induced TNF-alpha formation in human whole blood. | Homo sapiens | 13 | organism-based format | Scientific Literature |