| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA944268 | B | Inhibition of Plasmodium falciparum KAS3 expressed in Escherichia coli assessed as transfer of [1-14C]acetyl-CoA to [1-14C]acetyl-ACP | Plasmodium falciparum | 44 | assay format | Scientific Literature | ||
| 2. | ALA944269 | F | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum W2 by [3H]hypoxanthine uptake | Plasmodium falciparum | 44 | organism-based format | Scientific Literature | ||
| 3. | ALA944270 | F | Antimalarial activity against chloroquine-resistant Plasmodium falciparum D6 by [3H]hypoxanthine uptake | Plasmodium falciparum | 44 | organism-based format | Scientific Literature | ||
| 4. | ALA944271 | F | Antimalarial activity against Plasmodium falciparum TM91C235 by [3H]hypoxanthine uptake | Plasmodium falciparum | 19 | organism-based format | Scientific Literature | ||
| 5. | ALA944272 | A | Cytotoxicity against mouse J774.G8 cells after 72 hrs by MTS assay | Mus musculus | 22 | cell-based format | Scientific Literature | ||
| 6. | ALA944273 | A | Therapeutic index, ratio of IC50 for mice (Mus musculus) J774.G8 cells to IC50 for chloroquine-sensitive Plasmodium falciparum W2 | 22 | assay format | Scientific Literature | |||
| 7. | ALA1010085 | B | Inhibition of Escherichia coli FabH | Escherichia coli | 13 | assay format | Scientific Literature | ||
| 8. | ALA1010087 | B | Inhibition of Plasmodium falciparum FabH | Plasmodium falciparum | 10 | single protein format | Scientific Literature | ||
| 9. | ALA1010089 | B | Inhibition of Mycobacterium tuberculosis FabH | Mycobacterium tuberculosis | 14 | single protein format | Scientific Literature | ||
| 10. | ALA1010090 | B | Inhibition of Escherichia coli FabH assessed as restoration activity in presence of phosphate buffer after 16 hrs | Escherichia coli | 1 | assay format | Scientific Literature | ||
| 11. | ALA1010091 | F | Antibacterial activity against Escherichia coli tolC mutant | Escherichia coli | 6 | organism-based format | Scientific Literature | ||
| 12. | ALA1010092 | F | Antiplasmodial activity against chloroquine-sensitive Plasmodium falciparum D6 | Plasmodium falciparum | 6 | organism-based format | Scientific Literature | ||
| 13. | ALA2415166 | B | Inhibition of Pseudomonas aeruginosa PqsD using ACoA/beta-ketodecanoic acid as substrate assessed as HHQ formation incubated for 30 mins prior to ACoA addition followed by 10 mins after treated with beta-ketodecanoic acid measured for 40 mins | Pseudomonas aeruginosa | 8 | assay format | Scientific Literature | ||
| 14. | ALA2415169 | B | Binding affinity to Pseudomonas aeruginosa PqsD at 100 uM by surface plasmon resonance analysis in presence of ACoA | Pseudomonas aeruginosa | 1 | assay format | Scientific Literature | ||
| 15. | ALA2415170 | B | Inhibition of Pseudomonas aeruginosa PqsD using ACoA/beta-ketodecanoic acid as substrate assessed as HHQ formation incubated for 10 mins prior to ACoA/beta-ketodecanoic acid addition measured for 40 mins | Pseudomonas aeruginosa | 32 | assay format | Scientific Literature |
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