# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1948971 | B | Inhibition of Mycobacterium tuberculosis PTP-A using p-nitrophenyl phosphate as substrate at 25 uM measured for 10 mins by spectrofluorimetry | Mycobacterium tuberculosis | 100 | single protein format | Scientific Literature | ||
2. | ALA1948972 | B | Inhibition of Mycobacterium tuberculosis PTP-B using p-nitrophenyl phosphate as substrate at 25 uM measured for 10 mins by spectrofluorimetry | Mycobacterium tuberculosis | 100 | single protein format | Scientific Literature | ||
3. | ALA1948973 | B | Inhibition of Mycobacterium tuberculosis PTP-A using p-nitrophenyl phosphate as substrate measured for 10 mins by spectrofluorimetry | Mycobacterium tuberculosis | 33 | single protein format | Scientific Literature | ||
4. | ALA1948974 | B | Inhibition of Mycobacterium tuberculosis PTP-B using p-nitrophenyl phosphate as substrate measured for 10 mins by spectrofluorimetry | Mycobacterium tuberculosis | 33 | single protein format | Scientific Literature | ||
5. | ALA1948975 | B | Inhibition of human PTP1B expressed in Escherichia coli BL21 DE3 using p-nitrophenyl phosphate as substrate measured for 10 mins by spectrofluorimetry | Homo sapiens | 6 | assay format | Scientific Literature | ||
6. | ALA1948976 | B | Selectivity index, ratio of IC50 for human PTP1B to IC50 for Mycobacterium tuberculosis PTP-A | 3 | assay format | Scientific Literature | |||
7. | ALA1948978 | B | Competitive inhibition of Mycobacterium tuberculosis PTP-A using p-nitrophenyl phosphate as substrate measured for 10 mins by Lineweaver-Burk plot analysis | Mycobacterium tuberculosis | 3 | single protein format | Scientific Literature | ||
8. | ALA1948980 | B | Ratio of IC50 to Ki for Mycobacterium tuberculosis protein tyrosine phosphatase-A | Mycobacterium tuberculosis | 3 | single protein format | Scientific Literature | ||
9. | ALA1948982 | P | Solubility of the compound | 100 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA953320 | B | Inhibition of Mycobacterium tuberculosis recombinant protein tyrosine phosphatase assessed as enzyme activity at 25 uM | Mycobacterium tuberculosis | 37 | single protein format | Scientific Literature | ||
11. | ALA2395471 | B | Competitive inhibition of Yersinia enterocolitica recombinant YopH using pNPP as substrate after 10 mins by Line-weaver Burk plot analysis | Yersinia enterocolitica | 5 | single protein format | Scientific Literature | ||
12. | ALA2395472 | B | Inhibition of Yersinia enterocolitica recombinant YopH using pNPP as substrate at 25 uM after 10 mins by spectrophotometry | Yersinia enterocolitica | 12 | single protein format | Scientific Literature | ||
13. | ALA2395473 | B | Inhibition of Yersinia enterocolitica recombinant YopH using pNPP as substrate after 10 mins by spectrophotometry | Yersinia enterocolitica | 12 | single protein format | Scientific Literature | ||
14. | ALA2433214 | F | Antitubercular activity against Mycobacterium tuberculosis H37Rv assessed as growth inhibition after 12 to 28 days by Lowenstein-Jensen agar method | Mycobacterium tuberculosis | 23 | organism-based format | Scientific Literature | ||
15. | ALA2433215 | F | Antileishmanial activity against promastigote stage of Leishmania braziliensis H3 assessed as parasite growth inhibition after 72 hrs by Neubauer chamber counting method | Leishmania braziliensis | 23 | organism-based format | Scientific Literature | ||
16. | ALA2433216 | F | Potency index, ratio of griseofulvin MIC to compound MIC for Candida albicans MTCC 227 | Candida albicans | 10 | organism-based format | Scientific Literature | ||
17. | ALA2433217 | F | Antifungal activity against Aspergillus niger MTCC 282 assessed as growth inhibition by broth microdilution method | Aspergillus niger | 23 | organism-based format | Scientific Literature | ||
18. | ALA2433218 | F | Antifungal activity against Aspergillus clavatus MTCC 1323 assessed as growth inhibition by broth microdilution method | Aspergillus clavatus | 23 | organism-based format | Scientific Literature | ||
19. | ALA2433220 | F | Antifungal activity against Candida albicans MTCC 227 assessed as growth inhibition by broth microdilution method | Candida albicans | 23 | organism-based format | Scientific Literature | ||
20. | ALA2433224 | F | Antibacterial activity against Pseudomonas aeruginosa MTCC 2488 assessed as growth inhibition by broth microdilution method | Pseudomonas aeruginosa | 23 | organism-based format | Scientific Literature |