# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA963151 | B | Specific activity at molybdenum cofactor/metal-free precursor molybopterin bound human recombinant mARC1 expressed in Escherichia coli TP1000 assessed as reduction to guanabenz in complete reconstituted system containing microsomal cyt b5, NADH and microsomal NADH cyt b5 reductase per mg of protein at 0.5 mM by HPLC analysis | Homo sapiens | 1 | microsome format | Scientific Literature | ||
2. | ALA4614166 | A | Substrate activity at human mARC1 expressed in Escherichia coli assessed as turnover rates at 500 uM pre-incubated for 3 mins followed by NADH addition and measured after 15 mins by UV-Visible spectroscopy based NADH assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
3. | ALA4614171 | A | Substrate activity at human mARC2 expressed in Escherichia coli assessed as turnover rates at 500 uM pre-incubated for 3 mins followed by NADH addition and measured after 15 mins by UV-Visible spectroscopy based NADH assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
4. | ALA4614176 | A | Substrate activity at human mARC1 expressed in Escherichia coli assessed as turnover rates at 500 uM pre-incubated for 3 mins followed by NADH addition and measured after 15 mins by LC-MS analysis based assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
5. | ALA4614181 | A | Substrate activity at human mARC2 expressed in Escherichia coli assessed as turnover rates at 500 uM pre-incubated for 3 mins followed by NADH addition and measured after 15 mins by LC-MS analysis based assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
6. | ALA4651403 | F | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 4,309 | organism-based format | IMI-CARE SARS-CoV-2 Data |