# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1011807 | B | Displacement of [3H]UR-MK114 from neuropeptide Y1 receptor in human SK-N-MC cells | Homo sapiens | 5 | ALA1151759 | cell-based format | Scientific Literature | |
2. | ALA3750347 | B | Displacement of [3H]propionyl-pNPY from NPY1R (unknown origin) | Homo sapiens | 2 | ALA3745603 | single protein format | Scientific Literature | |
3. | ALA3750348 | B | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 6 | ALA3745603 | cell-based format | Scientific Literature | |
4. | ALA3750349 | B | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 secs by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 6 | ALA3745603 | cell-based format | Scientific Literature | |
5. | ALA3750350 | B | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 1 min by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 5 | ALA3745603 | cell-based format | Scientific Literature | |
6. | ALA3750351 | B | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 2 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 5 | ALA3745603 | cell-based format | Scientific Literature | |
7. | ALA3750352 | B | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 5 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 6 | ALA3745603 | cell-based format | Scientific Literature | |
8. | ALA3750353 | B | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 10 nM pNPY-induced Ca+2 response preincubated for 10 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 6 | ALA3745603 | cell-based format | Scientific Literature | |
9. | ALA3750359 | B | Displacement of [3H]UR-MK114 from NPY1R in human SK-N-MC cells by radioligand binding assay | Homo sapiens | 8 | ALA3745603 | cell-based format | Scientific Literature | |
10. | ALA3750361 | B | Displacement of [3H]UR-MK136 from NPY1R in human SK-N-MC cells by radioligand binding assay | Homo sapiens | 8 | ALA3745603 | cell-based format | Scientific Literature | |
11. | ALA3750362 | B | Displacement of [3H]propionyl-pNPY from NPY1R in human HEL cells preincubated for 30 mins followed by radioligand addition at 60 to 90 mins by flow cytometric analysis | Homo sapiens | 3 | ALA3745603 | cell-based format | Scientific Literature | |
12. | ALA3750365 | B | Displacement of [3H]propionyl-pNPY from NPY1R in human SK-N-MC cells compound treated immediately post radioligand treatment measured after 2 hrs by radioligand binding assay | Homo sapiens | 3 | ALA3745603 | cell-based format | Scientific Literature | |
13. | ALA3750366 | B | Displacement of Cy5-pNPY from human NPY2R expressed in CHO cells by flow cytometric analysis | Homo sapiens | 7 | ALA3745603 | cell-based format | Scientific Literature | |
14. | ALA3750367 | B | Displacement of Cy5-[K4]hPP from human NPY4R expressed in CHO cells by flow cytometric analysis | Homo sapiens | 7 | ALA3745603 | cell-based format | Scientific Literature | |
15. | ALA3750368 | B | Displacement of Cy5-pNPY from human NPY5R expressed in HEC cells by flow cytometric analysis | Homo sapiens | 7 | ALA3745603 | cell-based format | Scientific Literature | |
16. | ALA3750369 | B | Displacement of [3H]NPVF from human NPFF1 expressed in CHO cells by radioligand binding assay | Homo sapiens | 7 | ALA3745603 | cell-based format | Scientific Literature | |
17. | ALA3750524 | B | Displacement of [3H]EYF from human NPFF2 expressed in CHO cells by radioligand binding assay | Homo sapiens | 7 | ALA3745603 | cell-based format | Scientific Literature | |
18. | ALA3750539 | B | Antagonist activity at NPY1R in human HEL cells assessed as inhibition of 300 nM pNPY-induced Ca+2 response preincubated for 15 mins by Fura-2 dye based spectrofluorimetric analysis | Homo sapiens | 8 | ALA3745603 | cell-based format | Scientific Literature | |
19. | ALA3750541 | P | Chemical stability of the compound in phosphate buffer saline at pH 7 after after 48 hrs by RP-HPLC analysis | 3 | ALA3745603 | small-molecule physicochemical format | Scientific Literature |