# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA961557 | B | Inhibition of human sFRP1 expressed in human U2OS assessed as fold induction in luciferase activity at 15 uM by TCF-luciferase reporter gene assay relative to control | Homo sapiens | 11 | assay format | Scientific Literature | ||
2. | ALA961559 | B | Inhibition of human sFRP1 expressed in human U2OS assessed as luciferase activity by TCF-luciferase reporter gene assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
3. | ALA961560 | P | Aqueous solubility at pH 7.4 | 4 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA961561 | A | Metabolic stability in rat microsomes assessed as half life | Rattus norvegicus | 4 | microsome format | Scientific Literature | ||
5. | ALA961563 | A | Inhibition of CYP3A4 at 3 uM | 4 | single protein format | Scientific Literature | |||
6. | ALA961564 | A | Inhibition of CYP2D6 at 3 uM | 4 | single protein format | Scientific Literature | |||
7. | ALA961565 | A | Inhibition of CYP2C9 at 3 uM | 4 | single protein format | Scientific Literature | |||
8. | ALA961566 | F | Increase in bone formation in mouse calvaria assessed as increase in bone area at 5 uM after 7 days relative to control | Mus musculus | 1 | assay format | Scientific Literature | ||
9. | ALA961567 | F | Increase in bone formation in mouse calvaria assessed as number of osteoblast on bone surface at 5 uM after 7 days relative to control | Mus musculus | 1 | assay format | Scientific Literature |