| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA959580 | B | Inhibition of human recombinant cathepsin S by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 2. | ALA959581 | B | Inhibition of human recombinant cathepsin H by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 3. | ALA959582 | B | Selectivity for human recombinant cathepsin C over human recombinant cathepsin K | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 4. | ALA959583 | B | Inhibition of human recombinant cathepsin K by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 5. | ALA959584 | B | Inhibition of human recombinant cathepsin B by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 6. | ALA959585 | B | Blockade of conjugation of cathepsin C in human B721 cells to I125-labeled (S)-2-amino-N-((S)-1-(4-hydroxy-3-iodophenylsulfonyl)-5-phenylpent-1-en-3-yl)pentanamide pretreated for 30 mins before addition of I125-labeled (S)-2-amino-N-((S)-1-(4-hydroxy-3-iodophenylsulfonyl)-5-phenylpent-1-en-3-yl)pentanamide by SDS-PAGE | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA959586 | B | Inhibition of cathepsin C in human B721 cells by FACS assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA959588 | B | Inhibition of human recombinant cathepsin C by fluorescence assay | Homo sapiens | 3 | single protein format | Scientific Literature | ||
| 9. | ALA959589 | B | Inhibition of human recombinant cathepsin L by fluorescence assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA959590 | B | Selectivity for human recombinant cathepsin C over human recombinant cathepsin S | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 11. | ALA959591 | B | Selectivity for human recombinant cathepsin C over human recombinant cathepsin B | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 12. | ALA959592 | B | Selectivity for human recombinant cathepsin C over human recombinant cathepsin H | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 13. | ALA959593 | B | Selectivity for human recombinant cathepsin C over human recombinant cathepsin L | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 14. | ALA1244053 | A | Cytotoxicity against african green monkey BSC1 cells after 24 hrs by celltiter glo assay | Chlorocebus aethiops | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA1244054 | F | Antiplasmodial activity against Plasmodium falciparum schizont infected in human erythrocytes assessed as inhibition of ring-stage parasite growth at 1 to 50 uM after 24 by propidium iodide staining-based FACS analysis | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA1244056 | F | Antiplasmodial activity against Plasmodium falciparum schizont infected in human erythrocytes assessed as effect on schizont morphology at 1 to 50 uM after 24 by propidium iodide staining-based FACS analysis | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 17. | ALA1244058 | F | Antiplasmodial activity against Plasmodium falciparum schizont infected in human erythrocytes assessed as effect on parasite ring-to-schizont morphology at 1 to 50 uM after 24 by propidium iodide staining-based FACS analysis | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 18. | ALA1244065 | F | Antiplasmodial activity against Plasmodium falciparum infected in human erythrocytes assessed as blockade of parasite-mediated rupture of erythrocytes by Giemsa staining | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA1244066 | F | Antiplasmodial activity against Plasmodium falciparum infected in human erythrocytes assessed as effect on parasite morphology by Giemsa staining | Plasmodium falciparum | 2 | organism-based format | Scientific Literature | ||
| 20. | ALA1244067 | B | Inhibition of Plasmodium falciparum 3D7 PFD0230c by fluorescence spectrophotometry | Plasmodium falciparum 3D7 | 3 | single protein format | Scientific Literature |
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