# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA942267 | B | Inhibition of human recombinant NAT1 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's method | Homo sapiens | 18 | ALA1140849 | single protein format | Scientific Literature | |
2. | ALA942273 | B | Inhibition of Mycobacterium marinum recombinant NAT using isoniazid as substrate at 30 uM | Mycobacterium marinum | 15 | ALA1140849 | assay format | Scientific Literature | |
3. | ALA942274 | B | Inhibition of Pseudomonas aeruginosa recombinant NAT using isoniazid as substrate at 30 uM | Pseudomonas aeruginosa | 15 | ALA1140849 | single protein format | Scientific Literature | |
4. | ALA995941 | B | Inhibition of 6-His tagged recombinant c-Myc353-437 gene binding to Max(S) protein assessed as disruption of heterodimer formation by circular dichroism assay | 12 | ALA1140921 | assay format | Scientific Literature | ||
5. | ALA1646527 | B | Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysis | Bos taurus | 14 | ALA1641564 | single protein format | Scientific Literature | |
6. | ALA1762944 | B | Inhibition of diphenolase activity of mushroom tyrosinase preincubated with compound for 10 mins before addition of L-DOPA as substrate by spectrophotometric analysis | Agaricus bisporus | 12 | ALA1759867 | single protein format | Scientific Literature | |
7. | ALA1960748 | B | Inhibition of Dengue virus NS2B-NS3 protease using Abz-NleKRRS-3-(NO2)Y as substrate at 50 uM preincubated for 15 mins measured every sec for 15 mins by fluorimetric analysis | Dengue virus | 163 | ALA1955761 | assay format | Scientific Literature | |
8. | ALA1960749 | B | Inhibition of bovine plasma thrombin using Boc-Val-Pro-Arg-AMC as substrate at 25 uM preincubated for 15 mins measured after 10 mins by fluorimetric assay | Bos taurus | 163 | ALA1955761 | single protein format | Scientific Literature | |
9. | ALA1960750 | B | Inhibition of Escherichia coli MurA using PEP as substrate assessed as inorganic phosphate release at 25 uM preincubated for 10 mins measured after 60 mins by fluorimetric assay | Escherichia coli | 163 | ALA1955761 | assay format | Scientific Literature | |
10. | ALA1960751 | B | Inhibition of Escherichia coli MetAP at 10 uM after 15 mins by fluorescence analysis | Escherichia coli | 163 | ALA1955761 | assay format | Scientific Literature | |
11. | ALA3378822 | F | Antiviral activity against Chikungunya virus LR2006_OPY1 infected in african green monkey Vero cells assessed as reduction in virus-induced cytopathogenicity after 3 days by cell titer-blue fluorescent assay | Chikungunya virus | 20 | ALA3352512 | cell-based format | Scientific Literature | |
12. | ALA3378823 | F | Antiviral activity against Chikungunya virus LR2006_OPY1 infected in african green monkey Vero cells assessed as reduction in virus-induced cytopathogenicity at 100 ug/mL after 3 days by cell titer-blue fluorescent assay | Chikungunya virus | 15 | ALA3352512 | cell-based format | Scientific Literature | |
13. | ALA3378824 | A | Cytotoxicity against african green monkey Vero cells assessed as reduction in cell viability after 72 hrs by cell titer-blue fluorescent assay | Chlorocebus sabaeus | 20 | ALA3352512 | cell-based format | Scientific Literature | |
14. | ALA3991972 | B | Binding affinity to recombinant human His6 tagged c-Myc bHLH-LZ domain (353 to 439 residues) with GGCD extension at C-terminus expressed in Escherichia coli BL21 DE3 (pLysS) at 25 uM by fluorescence polarization assay | Homo sapiens | 13 | ALA3991942 | assay format | Patent Bioactivity Data | |
15. | ALA3991973 | B | Binding affinity to recombinant human full length His6 tagged Max (151 residues) expressed in Escherichia coli M15 (pRep4) at 25 uM by fluorescence polarization assay | Homo sapiens | 13 | ALA3991942 | assay format | Patent Bioactivity Data |