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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA2162815 F Up regulation of LDLR expression in human HepG2 cells at 10 uM after 12 hrs by RT-PCR relative to untreated control Homo sapiens 16 cell-based format Scientific Literature 2. ALA2162816 B Increase in AMPKalpha phosphorylation in human HepG2 cells at 10 uM after 4 hrs by Western blot analysis relative to untreated control Homo sapiens 4 cell-based format Scientific Literature 3. ALA2162817 F Increase in total AMPKalpha level in human HepG2 cells at 10 uM after 4 hrs by Western blot analysis relative to untreated control Homo sapiens 2 cell-based format Scientific Literature 4. ALA2162818 B Increase in AMPKalpha phosphorylation in human HepG2 cells at 10 uM after 4 hrs by Western blot analysis relative to untreated control relative to total AMPKalpha level Homo sapiens 2 cell-based format Scientific Literature 5. ALA2162819 B Induction of AMPKalpha phosphorylation in human HepG2 cells at 10 uM by Western blot analysis relative to untreated control Homo sapiens 1 cell-based format Scientific Literature 6. ALA2162820 B Induction of AMPKalpha phosphorylation in human HepG2 cells after 4 hrs by Western blot analysis relative to untreated control Homo sapiens 1 cell-based format Scientific Literature 7. ALA2162821 B Induction of AMPKalpha phosphorylation in rat L6 cells Rattus norvegicus 1 cell-based format Scientific Literature 8. ALA940345 F Induction of LDLR mRNA expression in human HepG2 cells after 12 hrs by RT-PCR assay relative to untreated control Homo sapiens 31 cell-based format Scientific Literature 9. ALA950527 F Induction of LDLR protein expression in human HepG2 cells at 10 ug/mL after 12 hrs by flow cytometry Homo sapiens 2 cell-based format Scientific Literature 10. ALA950528 F Reduction of blood cholesterol level in hyperlipidemic Sprague-Dawley rat at 100 mg/kg, po daily twice for 30 days relative to control Rattus norvegicus 2 organism-based format Scientific Literature 11. ALA950529 F Reduction of blood low density lipoprotein cholesterol level in hyperlipidemic Sprague-Dawley rat at 100 mg/kg, po daily twice for 30 days relative to control Rattus norvegicus 2 organism-based format Scientific Literature 12. ALA950530 F Reduction of blood cholesterol level in hyperlipidemic Sprague-Dawley rat at 100 mg/kg, po daily twice Rattus norvegicus 2 organism-based format Scientific Literature 13. ALA950531 F Reduction of blood low density lipoprotein cholesterol level in hyperlipidemic Sprague-Dawley rat at 100 mg/kg, po daily twice Rattus norvegicus 2 organism-based format Scientific Literature 14. ALA950532 F Induction of LDLR mRNA expression in hyperlipidemic Sprague-Dawley rat liver at 100 mg/kg, po daily twice for 30 days by RT-PCR relative to control Rattus norvegicus 2 organism-based format Scientific Literature 15. ALA951473 F Induction of HMG-CoA reductase mRNA expression in hyperlipidemic Sprague-Dawley rat liver at 100 mg/kg, po daily twice for 30 days by RT-PCR Rattus norvegicus 2 organism-based format Scientific Literature 16. ALA951474 T Toxicity in hyperlipidemic Sprague-Dawley rat assessed as weight loss at 100 mg/kg, po daily twice for 30 days Rattus norvegicus 1 organism-based format Scientific Literature 17. ALA951475 T Toxicity in hyperlipidemic Sprague-Dawley rat assessed as food intake reduction at 100 mg/kg, po daily twice for 30 days Rattus norvegicus 1 organism-based format Scientific Literature 18. ALA951476 T Toxicity in hyperlipidemic Sprague-Dawley rat assessed as liver and kidney function abnormalities at 100 mg/kg, po daily twice for 30 days Rattus norvegicus 1 organism-based format Scientific Literature 19. ALA951477 F Reduction of blood cholesterol level in hyperlipidemic Sprague-Dawley rat at 100 mg/kg, po daily twice for 17 days relative to control Rattus norvegicus 1 organism-based format Scientific Literature 20. ALA951478 F Reduction of blood low density lipoprotein cholesterol level in hyperlipidemic Sprague-Dawley rat at 100 mg/kg, po daily twice for 17 days relative to control Rattus norvegicus 1 organism-based format Scientific Literature