# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1006149 | Binding | Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR | Homo sapiens | 56 | ALA1140878 | cell-based format | Scientific Literature | |
2. | ALA1006150 | Binding | Channel opening activity at SUR2B/Kir6.2 potassium ATP channel in human TE671 cells assessed as isometric force by FLIPR in presence of glyburide | Homo sapiens | 53 | ALA1140878 | cell-based format | Scientific Literature | |
3. | ALA1006151 | Binding | Channel opening activity at SUR1/Kir6.2 potassium ATP channel in mouse beta-TC6 cells assessed as isometric force by FLIPR | Mus musculus | 7 | ALA1140878 | cell-based format | Scientific Literature | |
4. | ALA1006152 | Binding | Channel opening activity at SUR2A/Kir6.2 potassium ATP channel in african green monkey COS7 cells assessed as isometric force by FLIPR | Chlorocebus aethiops | 7 | ALA1140878 | cell-based format | Scientific Literature | |
5. | ALA1006153 | Binding | Selectivity ratio of EC50 for mouse SUR1/Kir6.2 potassium ATP channel to human SUR2B/Kir6.2 potassium ATP channel | 7 | ALA1140878 | assay format | Scientific Literature | ||
6. | ALA1006154 | Binding | Selectivity ratio of EC50 for african green monkey SUR2A/Kir6.2 potassium ATP channel to human SUR2B/Kir6.2 potassium ATP channel | 7 | ALA1140878 | assay format | Scientific Literature | ||
7. | ALA1006155 | Functional | Vasorelaxant activity in rat bladder assessed as inhibition of carbachol-induced contraction | Rattus norvegicus | 4 | ALA1140878 | tissue-based format | Scientific Literature | |
8. | ALA1006156 | Functional | Inhibition of acetic acid-induced unstable bladder contractions in Sprague-Dawley rat at 0.3 mg/kg/ml, iv by cytometry | Rattus norvegicus | 1 | ALA1140878 | organism-based format | Scientific Literature | |
9. | ALA1006959 | Functional | Inhibition of intravesical outflow obstruction-induced hypertrophy in Sprague-Dawley rat assessed as reduction in unstable bladder contractions at 3 mg/kg, po by cytometry | Rattus norvegicus | 1 | ALA1140878 | organism-based format | Scientific Literature |