# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA941171 | Binding | Inhibition of HIV1 LAI clade B reverse transcriptase RNase H activity by real time monitoring assay | Human immunodeficiency virus 1 | 20 | ALA1140907 | single protein format | Scientific Literature | |
2. | ALA941172 | Binding | Inhibition of HIV1 LAI clade C 93IN101 reverse transcriptase RNase H activity by real time monitoring assay | Human immunodeficiency virus 1 | 2 | ALA1140907 | single protein format | Scientific Literature | |
3. | ALA941173 | Binding | Inhibition of HIV1 LAI CRF01 A_E s93JP-NH1 reverse transcriptase RNase H activity by real time monitoring assay | Human immunodeficiency virus 1 | 2 | ALA1140907 | single protein format | Scientific Literature | |
4. | ALA941174 | Binding | Inhibition of murine leukemia virus reverse transcriptase by real time monitoring assay | Murine leukemia virus | 2 | ALA1140907 | assay format | Scientific Literature | |
5. | ALA941175 | Binding | Inhibition of Escherichia coli RNase H by real time monitoring assay | Escherichia coli | 2 | ALA1140907 | assay format | Scientific Literature | |
6. | ALA941176 | Binding | Inhibition of human RNase H1 by real time monitoring assay | Homo sapiens | 2 | ALA1140907 | single protein format | Scientific Literature | |
7. | ALA941177 | Binding | Inhibition of HIV1 integrase by real time monitoring assay | Human immunodeficiency virus 1 | 2 | ALA1140907 | single protein format | Scientific Literature | |
8. | ALA941178 | ADME | Cytotoxicity against CD4-CXCR4 expressing human NP2 cells at >25 uM by MTT assay | Homo sapiens | 2 | ALA1140907 | cell-based format | Scientific Literature | |
9. | ALA941179 | ADME | Cytotoxicity against T cells at >25 uM by MTT assay | 2 | ALA1140907 | cell-based format | Scientific Literature | ||
10. | ALA941180 | ADME | Cytotoxicity against IL2 and anti-CD3-stimulated CD4 expressing primary T cells at 25 to 30 uM by MTT assay | 2 | ALA1140907 | cell-based format | Scientific Literature | ||
11. | ALA941181 | Functional | Inhibition of HIV1 NL4-3 replication in CD4-CXCR4 expressing human NP2 cells assessed as decrease in p24 antigen production after 4 days by ELISA | Human immunodeficiency virus 1 | 1 | ALA1140907 | organism-based format | Scientific Literature | |
12. | ALA941182 | Functional | Inhibition of HIV1 NL4-3 replication in CD4 expressing human T cells assessed as decrease in p24 antigen production at 25 uM after 4 days by ELISA | Human immunodeficiency virus 1 | 1 | ALA1140907 | organism-based format | Scientific Literature |