# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA964195 | Binding | Inhibition of EGFR by SPA assay | 4 | ALA1153281 | single protein format | Scientific Literature | ||
2. | ALA964936 | Binding | Inhibition of ErbB2 by SPA assay | 4 | ALA1153281 | single protein format | Scientific Literature | ||
3. | ALA964937 | Binding | Induction of EGFR covalent modification assessed as alkylation after 3 hrs by LC/MS mass spectroscopy | 22 | ALA1153281 | single protein format | Scientific Literature | ||
4. | ALA964938 | Functional | Antiproliferative activity against human HN5 cells overexpressing EGFR after 3 days | Homo sapiens | 22 | ALA1153281 | cell-based format | Scientific Literature | |
5. | ALA964939 | Functional | Antiproliferative activity against human BT474 cells overexpressing ErbB2 after 3 days | Homo sapiens | 22 | ALA1153281 | cell-based format | Scientific Literature | |
6. | ALA964941 | ADME | Dose normalized AUC in mouse at 10 mg/kg, po after 6 hrs | Mus musculus | 10 | ALA1153281 | organism-based format | Scientific Literature | |
7. | ALA964942 | ADME | Protein binding in rat plasma by HPLC | Rattus norvegicus | 10 | ALA1153281 | cell-free format | Scientific Literature | |
8. | ALA964943 | ADME | Cytotoxicity against HFF | Homo sapiens | 22 | ALA1153281 | cell-based format | Scientific Literature |