# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA964155 | B | Binding affinity to dopamine D4 receptor | 3 | single protein format | Scientific Literature | |||
2. | ALA964156 | B | Binding affinity to dopamine D2 receptor | 3 | single protein format | Scientific Literature | |||
3. | ALA964158 | B | Binding affinity to rat sst1 receptor | Rattus norvegicus | 34 | single protein format | Scientific Literature | ||
4. | ALA964159 | B | Binding affinity to rat sst2 receptor | Rattus norvegicus | 18 | single protein format | Scientific Literature | ||
5. | ALA964160 | B | Selectivity for rat sst1 receptor over rat sst2 receptor | Rattus norvegicus | 7 | assay format | Scientific Literature | ||
6. | ALA964161 | B | Binding affinity to human sst1 receptor | Homo sapiens | 4 | single protein format | Scientific Literature | ||
7. | ALA964162 | B | Binding affinity to human sst2 receptor | Homo sapiens | 4 | single protein format | Scientific Literature | ||
8. | ALA964163 | B | Binding affinity to human sst3 receptor | Homo sapiens | 4 | single protein format | Scientific Literature | ||
9. | ALA964164 | B | Binding affinity to human sst4 receptor | Homo sapiens | 4 | single protein format | Scientific Literature | ||
10. | ALA964165 | B | Binding affinity to human sst5 receptor | Homo sapiens | 4 | single protein format | Scientific Literature | ||
11. | ALA964166 | F | Antagonist activity at rat sst1 receptor assessed as inhibition of forskolin-stimulated cAMP accumulation by luciferase assay | Rattus norvegicus | 2 | assay format | Scientific Literature | ||
12. | ALA964167 | F | Antagonist activity at human sst1 receptor assessed as inhibition of forskolin-stimulated cAMP accumulation by luciferase assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
13. | ALA964168 | B | Binding affinity to adrenergic alpha1 receptor | 2 | assay format | Scientific Literature | |||
14. | ALA964169 | A | Oral bioavailability in mouse at 30 umol/kg | Mus musculus | 2 | organism-based format | Scientific Literature | ||
15. | ALA964170 | A | Ratio of drug level in brain to plasma in mouse at 10 umol/kg, iv and 30 umol/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
16. | ALA964171 | A | Tmax in mouse at 10 umol/kg, iv and 30 umol/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
17. | ALA964172 | A | Apparent terminal half life in mouse plasma at 10 umol/kg, iv and 30 umol/kg, po | Mus musculus | 2 | organism-based format | Scientific Literature | ||
18. | ALA964173 | A | Inhibition of human CYP1A2 by microplate-based direct fluorometric assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
19. | ALA964174 | A | Inhibition of human CYP3A4 by microplate-based direct fluorometric assay | Homo sapiens | 2 | single protein format | Scientific Literature | ||
20. | ALA964175 | A | Inhibition of human CYP2C19 by microplate-based direct fluorometric assay | Homo sapiens | 2 | single protein format | Scientific Literature |