# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1028165 | F | Cognitive enhancing effect against scopolamine-induced acquisition memory deficit in mouse assessed as escape latency at 10 mg/kg, intragastric gavage after 24 hrs by step-down passive avoidance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
2. | ALA1015165 | B | Inhibition of AChE in rat cortex after 15 mins by modified Ellman method | Rattus norvegicus | 34 | assay format | Scientific Literature | ||
3. | ALA1015166 | B | Inhibition of BChE in rat serum after 15 mins by modified Ellman method | Rattus norvegicus | 34 | cell-free format | Scientific Literature | ||
4. | ALA1015167 | B | Selectivity ratio of IC50 for BChE in rat serum to IC50 for AChE in rat cortex | Rattus norvegicus | 34 | cell-free format | Scientific Literature | ||
5. | ALA1015168 | F | Cognitive enhancing effect against scopolamine-induced acquisition memory deficit in mouse assessed as times of step-down at 2 mg/kg, intragastric gavage after 24 hrs by step-down passive avoidance test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
6. | ALA1015169 | F | Cognitive enhancing effect against scopolamine-induced acquisition memory deficit in mouse assessed as times of step-down at 5 mg/kg, intragastric gavage after 24 hrs by step-down passive avoidance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA1015170 | F | Cognitive enhancing effect against scopolamine-induced acquisition memory deficit in mouse assessed as times of step-down at 10 mg/kg, intragastric gavage after 24 hrs by step-down passive avoidance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
8. | ALA1016049 | F | Cognitive enhancing effect against scopolamine-induced acquisition memory deficit in mouse assessed as escape latency at 2 mg/kg, intragastric gavage after 24 hrs by step-down passive avoidance test | Mus musculus | 3 | organism-based format | Scientific Literature | ||
9. | ALA1016050 | F | Cognitive enhancing effect against scopolamine-induced acquisition memory deficit in mouse assessed as escape latency at 5 mg/kg, intragastric gavage after 24 hrs by step-down passive avoidance test | Mus musculus | 1 | organism-based format | Scientific Literature | ||
10. | ALA3069984 | B | Binding affinity to acetylcholinesterase (unknown origin) | Homo sapiens | 58 | single protein format | Scientific Literature | ||
11. | ALA3069985 | B | Inhibition of acetylcholinesterase in Rattus norvegicus (rat) cortex by Ellman method | Rattus norvegicus | 45 | assay format | Scientific Literature | ||
12. | ALA5106126 | B | Inhibition of human serum recombinant AChE using acetylthiocholine iodide as a substrate incubated for 20 mins by DTNB reagent based Ellman's method | Homo sapiens | 11 | cell-free format | Scientific Literature | ||
13. | ALA5106128 | B | Inhibition of human serum recombinant BChE using butyrylthiocholine iodide as a substrate at 10 uM incubated for 20 mins by DTNB reagent based Ellman's method | Homo sapiens | 9 | cell-free format | Scientific Literature | ||
14. | ALA5106130 | B | Inhibition of human recombinant MAO-A assessed as reduction in 4-hydroxyquinoline level using kynuramine as a substrate at 10 uM preincubated for 5 mins followed by substrate addition by spectrofluorimetric analysis | Homo sapiens | 6 | single protein format | Scientific Literature | ||
15. | ALA5106131 | B | Inhibition of human recombinant MAO-B assessed as reduction in 4-hydroxyquinoline level using kynuramine as a substrate preincubated for 5 mins followed by substrate addition by spectrofluorimetric analysis | Homo sapiens | 7 | single protein format | Scientific Literature |