# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA1805383 | Functional | Inhibition of SHH pathway in mouse Shh Light2 cells after 40 hrs by Gli-dependent luciferase reporter gene assay | Mus musculus | 3 | ALA1799946 | cell-based format | Scientific Literature | |
2. | ALA1805384 | Binding | Inhibition of N-terminal SHH activated pathway in mouse C3H10T1/2 cells assessed as SAG-induced cell differentiation by alkaline phosphatase assay | Mus musculus | 3 | ALA1799946 | cell-based format | Scientific Literature | |
3. | ALA1805385 | Binding | Inhibition of N-terminal SHH activated pathway in mouse C3H10T1/2 cells assessed as SAG-induced cell differentiation at 1 uM by alkaline phosphatase assay | Mus musculus | 3 | ALA1799946 | cell-based format | Scientific Literature | |
4. | ALA1805386 | Binding | Inhibition of N-terminal SHH activated pathway in mouse C3H10T1/2 cells assessed as SAG-induced cell differentiation at 10 uM by alkaline phosphatase assay | Mus musculus | 3 | ALA1799946 | cell-based format | Scientific Literature | |
5. | ALA1805387 | Functional | Inhibition of SHH pathway in mouse Shh Light2 cells at 0.3 uM after 40 hrs by Gli-dependent luciferase reporter gene assay | Mus musculus | 3 | ALA1799946 | cell-based format | Scientific Literature | |
6. | ALA1805388 | Functional | Inhibition of SHH pathway in mouse Shh Light2 cells at 3 uM after 40 hrs by Gli-dependent luciferase reporter gene assay | Mus musculus | 3 | ALA1799946 | cell-based format | Scientific Literature | |
7. | ALA1805389 | Functional | Inhibition of SHH pathway in mouse Shh Light2 cells at 10 uM after 40 hrs by Gli-dependent luciferase reporter gene assay | Mus musculus | 3 | ALA1799946 | cell-based format | Scientific Literature | |
8. | ALA972423 | Binding | Inhibition of lipid-modified (octylated) form of SHH expressed in mouse s12 cells by luciferase reporter gene assay | 4 | ALA1138588 | cell-based format | Scientific Literature | ||
9. | ALA2032858 | Functional | Antiproliferative activity against SAG-induced rat cerebellar granule cell precursors by [3H]-thymidine incorporation assay | Rattus norvegicus | 8 | ALA2029339 | assay format | Scientific Literature | |
10. | ALA2033030 | Functional | Inhibition of SAG-induced differentiation of mouse mesenchymal pluripotent C3H10T1/2 cells to alkaline phosphatase positive oeseoblasts after 6 hrs | Mus musculus | 76 | ALA2029339 | cell-based format | Scientific Literature | |
11. | ALA2033031 | Functional | Inhibition of Smo-mediated Hh signaling in human Shh-light2 cells by luciferase reporter gene assay | Homo sapiens | 68 | ALA2029339 | cell-based format | Scientific Literature | |
12. | ALA2033036 | Binding | Displacement of BODIPY-labelled cyclopamine from human Smo receptor expressed in HEK293 cells after 2 hrs by fluorescence microscopy | Homo sapiens | 8 | ALA2029339 | cell-based format | Scientific Literature | |
13. | ALA4303805 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
14. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
15. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
16. | ALA4808149 | Binding | Enzymatic assay of human HDAC6 with commercial peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 | |
17. | ALA4808150 | Binding | Enzymatic assay of human HDAC6 with custom peptide substrate | Homo sapiens | 5,603 | ALA4808148 | single protein format | Fraunhofer HDAC6 |